Advanced Functional Materials, EarlyView.Platinum‐Copper bimetallic nanoparticles may evolve depending on their synthesis under tumor microenvironment conditions and play a dual role as chemotherapeutic agents after releasing Cu ions and as near infrared photothermal agents with the Pt‐rich remaining frames.
Jose I. Garcia‐Peiro +7 more
wiley +1 more source
Essential Role for the dsRNA-Dependent Protein Kinase PKR in Innate Immunity to Viral Infection [PDF]
, 2000 Siddharth Balachandran +6 more
openalex +1 more source
Magnetically Guided Mechanoactive Mineralization Scaffolds for Enhanced Bone Regeneration
Advanced Functional Materials, EarlyView.A 3D‐printed ‘rebar‐concrete’ inspired scaffold (PGS‐P@MGel) synergizes spontaneous biomineralization with magneto‐mechanical stimulation through PDA@Fe3O4‐embedded hydrogel. This dual biointerface activates Piezo1/β‐catenin/YAP mechanotransduction axis, enhancing BMSCs osteogenesis and angiogenesis simultaneously.
Xuran Guo +10 more
wiley +1 more source
Gram-negative Bacteria-binding Protein, a Pattern Recognition Receptor for Lipopolysaccharide and β-1,3-Glucan That Mediates the Signaling for the Induction of Innate Immune Genes in Drosophila melanogaster Cells [PDF]
, 2000 Yong Sik Kim +8 more
openalex +1 more source
Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks
Advanced Functional Materials, EarlyView.This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson +12 more
wiley +1 more source
Anopheles gambiae pilot gene discovery project: Identification of mosquito innate immunity genes from expressed sequence tags generated from immune-competent cell lines [PDF]
, 2000 George Dimopoulos +11 more
openalex +1 more source
Advanced Functional Materials, EarlyView.This study presents a microfluidic brain microvascular network‐on‐chip (BMVasChip) to investigate endothelial barrier dysfunction caused by flavivirus non‐structural protein 1 (NS1), including virus‐ and time‐dependent vascular damage, leakiness, and dysfunction.
Monika Rajput +5 more
wiley +1 more source
Genetically Determined Disparate Innate and Adaptive Cell-Mediated Immune Responses to PulmonaryMycobacterium bovisBCG Infection in C57BL/6 and BALB/c Mice [PDF]
, 2000 Julia Wakeham, Jun Wang, Zhou Xing
openalex +1 more source