Results 181 to 190 of about 742,081 (332)

Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury

Advanced Functional Materials, EarlyView.
After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen, Yvonne Shen, Yutong Shao, Tenghuan Ge, Haowen Qiao, Shangzhou Xia, Yafei Qu, Yuanpu Chiu, Ying Qin, Zhen Zhao   +9 more
wiley   +1 more source

Type 1 Interferon (IFNα/β) and Type 2 Nitric Oxide Synthase Regulate the Innate Immune Response to a Protozoan Parasite

, 1998
Andreas Diefenbach, Heike Schindler, Norbert Donhauser, E Lorenz, Tamás Laskay, John D. MacMicking, Martin Röllinghoff, Ion Gresser, Christian Bogdan   +8 more
openalex   +1 more source

T cell receptor-dependent activation of human lymphocytes through cell surface ganglioside GT1b: implications for innate immunity [PDF]

, 2000
Jack F. Bukowski, Maria Grazia Roncarolo, Hergen Spits, Michael S. Krangel, Craig T. Morita, Michael B. Brenner, Hamid Band   +6 more
openalex   +1 more source

Metal Nanoclusters for Cancer Imaging and Treatment

Advanced Functional Materials, EarlyView.
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu, Ziping Wang, Qiaofeng Yao, Ping Zhang, Jianping Xie, Xun Yuan   +5 more
wiley   +1 more source

Evolution and phylogeny of defense molecules associated with innate immunity in horseshoe crab

, 1998
Shun-ichiro Kawabata
openalex   +1 more source

Negative selection of B lymphocytes: a novel role for innate immunity [PDF]

, 2000
Jennifer L. Gommerman, Michael C. Carroll   +1 more
openalex   +1 more source

Antibody‐Programmable Bimetallic Nanozymes for Transcriptional Blockade Therapy in HER2/ER‐Positive Breast Cancer

Advanced Functional Materials, EarlyView.
Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao, Tong Ye, Mingjiang Liu, Jingchao Gao, Lian Tan, Qian Dong, Qingbo Lv, Qianqian Ye, Yu Wang   +8 more
wiley   +1 more source

C-Reactive Protein Binds to Apoptotic Cells, Protects the Cells from Assembly of the Terminal Complement Components, and Sustains an Antiinflammatory Innate Immune Response [PDF]

, 2000
Debra Gershov, SunJung Kim, Nathan Brot, Keith B. Elkon   +3 more
openalex   +1 more source

Innate Immunity of the Lung [PDF]

Journal of Innate Immunity, 2019
Catherine M. Greene, Pieter S. Hiemstra   +1 more
openaire   +3 more sources

Aptamer Functionalized Hydrogel Dressings for Post‐Surgery Tumor Recurrence Inhibition and Tissue Reconstruction

Advanced Functional Materials, EarlyView.
Post‐surgical tumor therapy struggles with recurrence and inefficient healing. Anti‐tumor DNA aptamer functionalized gelatin hydrogels, Apt‐GelMA, simultaneously address both issues by suppressing tumor regrowth via targeted tumor cell inhibition and enhancing wound healing through improved cell adhesion and migration. Their biocompatibility, stability,
Tianyue Li, Xin‐Yi Qian, Zi‐Yuan Li, Hao‐Wen Li, Poh‐Ching Tan, Chenghuizi Hu, Jiajun Jin, Shuang‐Bai Zhou, Qing‐Feng Li, He Tian, Junji Zhang, Itamar Willner   +11 more
wiley   +1 more source