Results 241 to 250 of about 131,532 (293)

Effect of Aspirin Challenge on Innate Lymphoid Cells in Asthma Patients With Aspirin Hypersensitivity. [PDF]

Eur J Immunol
Kacorzyk R, Jakiela B, Maciejska A, Węgrzyn AS, Ćmiel A, Sanak M, Mastalerz L.   +6 more
europepmc   +1 more source

Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema

Allergy, EarlyView.
This study performed an unbiased molecular profiling of CHE patients across diverse etiologies to identify shared pathogenic drivers and evaluate the impact of IL‐4Rα blockade via dupilumab over 16 weeks. CHE shows a mixed immune signature involving type 1, 2, and 3 pathways with features of atopic dermatitis and psoriasis.
Perrine Gery, Rüçhan Ekren, Emilie Bérard, Aurélie Du‐Thanh, Hugo Rimet, Fatma Jendoubi, Vanina Lenief, Nadia Raison‐Peyron, Amel Bouznad, Maria P. Konstantinou, Jonathan Rioual, Lilian Basso, Juliette Mouiren, Manon Boussier, Brigitte Milpied, Cristina Bulai Livideanu, Louise Jaulent, Florence Hacard, Marine A. Lefevre, Audrey Nosbaum, Julien Seneschal, Marc Vocanson, Carle Paul, Nicolas Gaudenzio, Marie Tauber, on behalf of the French Atopic Dermatitis Network from de GREAT Research group   +25 more
wiley   +1 more source

Development and computational analysis of high dimensional spectral flow cytometry data for the resolution of innate lymphoid cells in the mammary tumor microenvironment. [PDF]

Front Immunol
Seo H, Xue J, Huang Q, Kinzel M, Verma A, Huynh N, Jamila Ikra Z, Mahoney DJ, Lee J, Morrissy S, Jacquelot N.   +10 more
europepmc   +1 more source

Early Epidemiologic and Immune Predictors of Atopic Dermatitis: Reduced Cord Blood Regulatory B10 Cells in the Munich Atopy Prediction Study (MAPS)

Allergy, EarlyView.
In this prospective birth cohort from Munich, comprehensive clinical assessments and longitudinal lifestyle questionnaires were combined with cord blood immune profiling. Infants who later developed AD showed altered cord blood immune signatures, including reduced CD4+ T cells, increased B cells and markedly decreased Breg cells. Epidemiologic factors,
S. Preis, S. Kaesler, M. Koeberle, M. Hils, B. Evers, R. L. Silva, Y. Skabytska, L. Schellenberger, H. Hufnagel, M. Schielein, B. Kuschel, Y. Amar, A. Zink, T. Biedermann, Z. Kurgyis   +14 more
wiley   +1 more source

BACH2 drives the development and function of group 2 innate lymphoid cells. [PDF]

Sci Adv
Liu G, Wang Y, Yi X, Wang J, Zhang J, Feng X, Wang H, Chen C, Liu Q, Wang J, Zhou J.   +10 more
europepmc   +1 more source

IL‐33 Drives Inflammatory Changes and Extracellular Trap Formation in Eosinophils Involving Oxidised LDL and Complement Pathways

Allergy, EarlyView.
IL‐33 induces inflammatory gene signatures in eosinophils, characterised by the upregulation of cell surface markers, inflammatory mediators and regulatory factors, all of which were also observed in nasal polyp‐derived eosinophils. Ox‐LDL and complement fragments (C3a and C5a) promote eosinophil adhesion and survival.
Emiko Matsuyama, Jun Miyata, Takao Mochimaru, Ryuta Onozato, Yo Otsu, Hisashi Sasaki, Keeya Sunata, Shinichi Okuzumi, Katsunori Masaki, Hiroki Kabata, Keinosuke Hizuka, Yoshinori Hasegawa, Ryo Konno, Yusuke Kawashima, Makoto Arita, Shigeharu Ueki, Koichi Fukunaga   +16 more
wiley   +1 more source

Unspoken words: decoding the dialog between type 2 innate lymphoid cells and T cells. [PDF]

Front Immunol
Ikra ZJ, Huang Q, Yu H, Belz GT, Jenne CN, Jacquelot N.   +5 more
europepmc   +1 more source

Polypropylene Nanoplastic Exposure to Respiratory Epithelial Barrier‐On‐Chip and Interfacial Interactions With Human Serum Albumin

Allergy, EarlyView.
Exposure to 305 nm PP NPs significantly disrupts the airway barrier‐on‐chip, reducing TEER, suppressing ZO‐1/ACE2 expression, and triggering ROS‐mediated apoptosis. In biological media, PP NPs exhibit a biphasic adsorption pattern, leading to the formation of a protein corona that increases their size to 364 nm.
Omur Sert, Eyup Bilgi, Reyhan Coban, Pelin Saglam‐Metiner, Basar Dogan, Zeynep Imir‐Tekneci, Suleyman Selim Cinaroglu, Ozlem Goksel, Ceyda Oksel Karakus, Ozlem Yesil‐Celiktas   +9 more
wiley   +1 more source

Human type-1 innate lymphoid cells control leukemia stem cell differentiation and limit acute myeloid leukemia development. [PDF]

Nat Commun
Li Z, Ma R, Tang H, Liu N, Zhang J, Marcucci G, Caligiuri MA, Yu J.   +7 more
europepmc   +1 more source

Involvement of increased arginase-1^<b>+</b> group 2 innate lymphoid cells and myeloid-derived suppressor cells in endometrial carcinoma: A pilot study. [PDF]

J Int Med Res
Gong Z, Lu Z, Pan A, Wang H, Yi H, Guo P, Bi K, Li X, Chen Y, Xu Y, Cao Y, Li C, Jiang H.   +12 more
europepmc   +1 more source