Results 101 to 110 of about 2,229,414 (244)

Redox-signaling in innate immune memory: Similar mechanisms in animals/humans and plants

open access: yesRedox Biology
Plants and animals/humans have evolved sophisticated innate immune systems to cope with microbial attack. Innate immunity implies the presence of membrane-located and intracellular receptors to recognize compounds released by damage or by invading ...
Christian Lindermayr   +1 more
doaj   +1 more source

Memory CD8+ T Cells: Orchestrators and Key Players of Innate Immunity?

open access: yesPLoS Pathogens, 2016
Over the past decades, the dichotomy between innate and adaptive immune responses has largely dominated our understanding of immunology. Upon primary encounter with microbial pathogens, differentiation of adaptive immune cells into functional effectors ...
Grégoire Lauvau, Stanislas Goriely
doaj   +1 more source

Chemical Strategies for Multistimuli Responsive Dynamic Covalent Materials in Regenerative Medicine

open access: yesAdvanced Healthcare Materials, EarlyView.
Multistimuli responsive dynamic covalent materials integrate reversible chemistry with the complex chemical, mechanical, and biochemical cues of regenerative environments. This review highlights chemical strategies based on orthogonal dynamic bonds, multicomponent networks, and hierarchical architectures to regulate mechanics, degradation, and ...
Saurabh Joshi   +2 more
wiley   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

open access: yesAdvanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song   +14 more
wiley   +1 more source

Phase Engineering of Nanomaterials (PEN): Evolution, Current Challenges, and Future Opportunities

open access: yesAdvanced Materials, EarlyView.
This review summarizes the synthesis, phase transition, advanced characterization spanning ex situ to in situ and operando techniques, and diverse applications of phase engineering of nanomaterials (PEN). It further outlines key challenges and future opportunities, such as phase stability, architecture control, and artificial intelligence (AI)‐driven ...
Ye Chen   +7 more
wiley   +1 more source

Can Elastomers Combine Stiffness, Toughness and Fatigue Resistance?

open access: yesAdvanced Materials, EarlyView.
This review studies how the molecular and macroscopic architecture of elastomers influence their mechanical properties including: stiffness, stretchability, toughness, fatigue resistance, and damping behavior. By linking the structure to performance, it proposes design principles for advanced elastomeric systems that combine mechanical properties ...
Eva Baur, Esther Amstad
wiley   +1 more source

Cytomegalovirus mediates expansion of IL-15-responsive innate-memory cells with SIV killing function. [PDF]

open access: yesJ Clin Invest, 2021
Méndez-Lagares G   +13 more
europepmc   +1 more source

Autonomous Folding of Soft Matter From Living Polymers

open access: yesAdvanced Materials, EarlyView.
Origami structures are endowed with “living” polymer creases that grow, remodel, and stiffen in response to nutrient solutions. This post‐fabrication growth enables autonomous folding, iterative regrowth, and mechanical tuning involving origami assemblies, such as cranes, Miura‐ori tessellations, rigid and non‐rigid square‐twist patterns, establishing ...
Jiahe Huang   +6 more
wiley   +1 more source

The impact of mycobacteria-induced trained immunity on SARS-CoV-2 vaccine responses

open access: yesFrontiers in Immunology
IntroductionBeyond the role of Bacillus Calmette-Guérin (BCG) for tuberculosis prevention, BCG has demonstrated heterologous protective effects. The global health crisis caused by the SARS-CoV-2 virus led to research on whether BCG-induced trained ...
Lidia Sánchez-Morales   +20 more
doaj   +1 more source

The commensal bacterium Lactiplantibacillus plantarum imprints innate memory-like responses in mononuclear phagocytes. [PDF]

open access: yesGut Microbes, 2021
Pellon A   +24 more
europepmc   +1 more source

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