Results 121 to 130 of about 9,113,445 (285)
Early embryonic cell fate and lineage specification is tightly regulated in the preimplantation mammalian embryo. Here, the authors quantitatively examine the ratio of epiblast to primitive endoderm lineages in the blastocyst and show composition of the ...
Néstor Saiz +3 more
doaj +1 more source
Oct4 is required for lineage priming in the developing inner cell mass of the mouse blastocyst
The transcription factor Oct4 is required in vitro for establishment and maintenance of embryonic stem cells and for reprogramming somatic cells to pluripotency. In vivo, it prevents the ectopic differentiation of early embryos into trophoblast. Here, we
Etienne-Dumeau, Charles +12 more
core +1 more source
Cell therapies typically rely on cold‐chain logistics and cryopreservation, limiting access and compromising cell quality. Here, a dual‐chamber device separates an oxygen‐supplying chamber from a hyaluronic acid cargo chamber, sustaining oxygen delivery for over 70 h and enabling ambient‐temperature shipment.
Daniel A. Domingo‐Lopez +9 more
wiley +1 more source
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal +21 more
wiley +1 more source
Non-smooth nonlinearities as restoring forces in a mass-in-mass cell
International audienceThe energy exchanges between particles of a mass-in-mass cell with nonlinear restoring forcing function are studied. Two types of non-smooth compound nonlinearities are considered as restoring forcing function acting on the inner ...
Dufour, Régis +3 more
core +1 more source
Genetically Programmed Shape‐Morphing of Engineered Living Materials
Here, bacterial and mammalian engineered living materials (ELMs) are presented, in which living cells direct genetically programmed and enzymatically mediated shape‐morphing. The resulting deformation and shape‐recovery can be actuated in a genetically controlled manner by an ELM incorporating out‐of‐equilibrium counteracting biochemical reactions with
Jan Becker +7 more
wiley +1 more source
FM1-43 reveals membrane recycling in adult inner hair cells of the mammalian cochlea [PDF]
Neural transmission of complex sounds demands fast and sustained rates of synaptic release from the primary cochlear receptors, the inner hair cells (IHCs). The cells therefore require efficient membrane recycling.
Ashmore, JF +2 more
core
Nitride MXenes remain constrained by a persistent gap between computational prediction and experimental realization. This Review identifies the thermodynamic, kinetic, and chemical barriers limiting their synthesis, critically evaluates emerging fabrication routes, and proposes a multidimensional computational‐experimental framework to accelerate the ...
Naresh Varnakavi, Masoud Soroush
wiley +1 more source
2k-inner products and 2k-Riemannian metrics [PDF]
The notion of 2k-inner product is introduced as a generalization of usual inner product and Q-inner product([4]-[8]). As a consequence, is defined the notion of 2k-normed space and some properties, e.g. uniformly convexity, Gâteaux differentiability and
Dragomir, Sever S, Crasmareanu, Mircea
core +1 more source
This study was carried out to determine the effect of the duration of exposure to an infrared 1.48 μm diode laser, on the number of cells in the inner cell mass and the trophectoderm of blastocysts following laser-assisted embryo biopsy.
Phakphum Phophong +2 more
doaj

