Results 151 to 160 of about 1,143 (172)

Innexins form two types of channels [PDF]

open access: yesFEBS Letters, 2007
Injury to the central nervous system triggers glial calcium waves in both vertebrates and invertebrates. In vertebrates the pannexin1 ATP‐release channel appears to provide for calcium wave initiation and propagation. The innexins, which form invertebrate gap junctions and have sequence similarity with the pannexins, are candidates to form non ...
Bao, Li   +5 more
exaly   +5 more sources

Connexins, innexins and pannexins: Bridging the communication gap [PDF]

open access: yesBiochimica Et Biophysica Acta - Biomembranes, 2005
Multicellular organisms have evolved different mechanismsof intercellular communication, the most direct and quickest ofwhich is through channels that link the cytoplasms of adjacentcells. In plants, a cytoplasmic continuity exists throughelongated cytoplasmic bridges termed plasmodesmata, whichcross the thick cell walls surrounding plant cells.
Thomas White   +2 more
exaly   +6 more sources

Gap Junction Channels of Innexins and Connexins: Relations and Computational Perspectives [PDF]

open access: yesInternational Journal of Molecular Sciences, 2019
Gap junction (GJ) channels in invertebrates have been used to understand cell-to-cell communication in vertebrates. GJs are a common form of intercellular communication channels which connect the cytoplasm of adjacent cells. Dysregulation and structural alteration of the gap junction-mediated communication have been proven to be associated with a ...
Pierre Baldi   +2 more
exaly   +7 more sources

Sequence and Phylogenetic Analyses of 4 TMS Junctional Proteins of Animals: Connexins, Innexins, Claudins and Occludins

open access: yesJournal of Membrane Biology, 2003
Connexins and probably innexins are the principal constituents of gap junctions, while claudins and occludins are principal tight functional constituents. All have similar topologies with four a-helical transmembrane segments (TMSs), and all exhibit well-
Milton Saier, Nalin M Kumar
exaly   +2 more sources
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Innexins in C. elegans

Cell Communication and Adhesion, 2001
Innexins are functionally analogous to the vertebrate connexins, and the innexin family of gap junction proteins has been identified in many invertebrates, including Drosophila and C. elegans. The genome sequencing project has identified 25 innexins in C. elegans.
T, Starich   +3 more
exaly   +3 more sources

Innexins Ogre and Inx2 are required in glial cells for normal postembryonic development of the Drosophila central nervous system [PDF]

open access: yesJournal of Cell Science, 2013
Innexins are one of two gene families that have evolved to permit neighbouring cells in multicellular systems to communicate directly. Innexins are found in prechordates and persist in small numbers in chordates as divergent sequences termed pannexins ...
Richard A Baines, Pauline Phelan
exaly   +2 more sources

Connexins, pannexins, innexins: novel roles of “hemi-channels” [PDF]

open access: yesPflugers Archiv European Journal of Physiology, 2008
The advent of multicellular organisms, some 800 million years ago, necessitated the development of mechanisms for cell-to-cell synchronization and for the spread of signals across increasingly large cell populations [168, 185]. Many structures and mechanisms have evolved to achieve such functions [4, 15].
David C Spray, Eliana Scemes
exaly   +5 more sources

Unnexins: Homologs of innexin proteins in Trypanosomatidae parasites

Journal of Cellular Physiology, 2021
AbstractLarge‐pore channels, including those formed by connexin, pannexin, innexin proteins, are part of a broad family of plasma membrane channels found in vertebrates and invertebrates, which share topology features. Despite their relevance in parasitic diseases such as Chagas and malaria, it was unknown whether these large‐pore channels are present ...
Juan, Güiza   +11 more
openaire   +2 more sources

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