Results 91 to 100 of about 242,551 (265)

Modeling adoption of innovations in agriculture using discrete choice models [PDF]

open access: yes
This paper is concerned with the development of varieties and fertilization techniques of greenhouse tomatoes, and their spatial diffusion in the northwestern region of the Negev in Israel.
Shlomo Bekhor   +2 more
core  

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Business Process Innovation using the Process Innovation Laboratory [PDF]

open access: yes, 2006
Most organizations today are required not only to establish effective business processes but they are required to accommodate for changing business conditions at an increasing rate. Many business processes extend beyond the boundary of the enterprise into the supply chain and the information infrastructure therefore is critical.
openaire   +2 more sources

Governance of regional innovations towards sustainability

open access: yes, 2008
This paper addresses the governance of regional innovations towards sustainability. From the literature it is clear that variety is a major source of innovations: innovations come into being in interplay between a variety of public and private actors who
Termeer, C.J.A.M., Kranendonk, R.P.
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Public research and industrial innovations in Germany [PDF]

open access: yes
This paper deals with the effects of publicly funded research at universities, polytechnics and federal research labs on industrial innovations in Germany.
Beise, Marian, Stahl, Harald
core  

Search Balance and Product and Process Innovations

open access: yes
Firms’ search for external knowledge is one aspect of knowledge integration in the innovation process. The literature has investigated innovation and the breadth of search in different information channels.
Backfisch, Martin
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

The diffusion of process innovations

open access: yes
THE DIFFUSION OF PROCESS INNOVATIONS The diffusion of process innovations (-
Davies, Stephen
core  

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