Inorganic pyrophosphatases (PPases) catalyze an essential reaction, namely, the hydrolysis of PPi, which is formed in large quantities as a side product of numerous cellular reactions.
Evgeniya A. Malykh +6 more
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The inorganic pyrophosphatase activity of erythrocytes in favism
Inorganic pyrophosphatase activity of erythrocytes was found to be decreased in subjects affected by the glucose-6-phosphate dehydrogenase deficiency. During the acute hemolytic episode of favism, pyrophosphatase activity shows a further critical fall.
Güngör Ernişli, Faolo Brunetti
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Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates. [PDF]
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Rolfes RJ.
europepmc +2 more sources
Escherichia coli DnaE Polymerase Couples Pyrophosphatase Activity to DNA Replication. [PDF]
DNA Polymerases generate pyrophosphate every time they catalyze a step of DNA elongation. This elongation reaction is generally believed as thermodynamically favoured by the hydrolysis of pyrophosphate, catalyzed by inorganic pyrophosphatases.
Fabio Lapenta +7 more
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Mutagenesis Reveals That the OsPPa6 Gene Is Required for Enhancing the Alkaline Tolerance in Rice
Alkaline stress (AS) is one of the abiotic stressful factors limiting plant’s growth and development. Inorganic pyrophosphatase is usually involved in a variety of biological processes in plant in response to the abiotic stresses.
Bing Wang +8 more
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PPA1, an energy metabolism initiator, plays an important role in the progression of malignant tumors
Inorganic pyrophosphatase (PPA1) encoded by PPA1 gene belongs to Soluble Pyrophosphatases (PPase) family and is expressed widely in various tissues of Homo sapiens, as well as significantly in a variety of malignancies.
Shuying Wang +11 more
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A combination of thermostable enzymes has been developed that produces higher quality cycle sequences. Thermo Sequenase™ DNA polymerase is a thermostable enzyme engineered to catalyze the incorporation of ddNTPs with an efficiency several thousandfold ...
P.B. Vander Horn +12 more
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Inactivation of yeast inorganic pyrophosphatase by organic solvents
A number of application for enzymes in organic solvents have been developed in chemical processing, food related conversions and analyses. The only unsolved problem related to nonaqueous enzymology is the notion that enzymes in organic solvent are mostly
Rodrigo Grazinoli-Garrido +1 more
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Reconstitution of Biological Molecular Generators of Electric Current Inorganic Pyrophosphatase
Proteoliposomes have been reconstituted from soy‐bean phospholipids (asolectin) and inorganic pyrophosphatase isolated from Rhodospirillum rubrum chromatophores.
KONDRASHIN A.A. +3 more
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Enhancement of the rate of pyrophosphate hydrolysis by nonenzymatic catalysts and by inorganic pyrophosphatase. [PDF]
To estimate the proficiency of inorganic pyrophosphatase as a catalyst, 31P NMR was used to determine rate constants and thermodynamics of activation for the spontaneous hydrolysis of inorganic pyrophosphate (PPi) in the presence and absence of Mg2+ at ...
Stockbridge RB, Wolfenden R.
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