Results 31 to 40 of about 378,797 (150)

A computational analysis reveals eight novel high-risk single nucleotide variants of human tumor suppressor LHPP gene

open access: yesEgyptian Journal of Medical Human Genetics, 2023
Background LHPP is a tumor suppressor protein associated with various malignancies like liver, oral, pharyngeal, bladder, cervical, and gastric cancers through controlling various pathways.
Tasmiah Feroz, Md. Kobirul Islam
doaj   +1 more source

Aggregation-Induced Emission of Au/Ag Alloy Nanoclusters for Fluorescence Detection of Inorganic Pyrophosphate and Pyrophosphatase Activity

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
The development of sensitive and accurate detection of inorganic pyrophosphate (PPi) and pyrophosphatase activity (PPase) is important as they play vital roles in biological systems.
Zhongli Lei   +4 more
doaj   +1 more source

An IscS Persulfide Donates the Sulfur for Ribosomal Protein uL16 Thioamidation

open access: yesAngewandte Chemie, EarlyView.
YcaO‐catalyzed thioamidation of the ribosomal subunit protein uL16 is widespread in Pseudomonadota bacteria. We identify the iron–sulfur cluster cysteine desulfurase IscS as the sulfur donor via an IscS persulfide and observe direct IscS–uL16 interactions.
Yanqing Xue   +2 more
wiley   +2 more sources

Hydrolysis of nucleoside di- and triphosphates by crystalline preparations of yeast inorganic pyrophosphatase [PDF]

open access: yes, 1960
1. 1. Crystalline preparations of yeast inorganic pyrophosphatase catalyze phosphate liberation from ATP and ADP, as well as from pyrophosphate, in the presence of zinc ions.2. 2.
Schlesinger, Milton J., Coon, Minor J.
core   +1 more source

The Role of the C-terminus in Bacillus subtilis inorganic pyrophosphatase activity [PDF]

open access: yes, 2003
Inorganic pyrophosphatases hydrolyse inorganic pyrophosphate ensuring that the pool of phosphate is continuously available in a cell for subsequent metabolic reactions.
Konopka, Monika
core   +7 more sources

Tetrameric Structures of Inorganic CBS-Pyrophosphatases from Various Bacterial Species Revealed by Small-Angle X-ray Scattering in Solution

open access: yesBiomolecules, 2020
Quaternary structure of CBS-pyrophosphatases (CBS-PPases), which belong to the PPases of family II, plays an important role in their function ensuring cooperative behavior of the enzymes.
Liubov A. Dadinova   +4 more
doaj   +1 more source

LHPP-mediated inorganic pyrophosphate hydrolysis-driven lysosomal acidification in astrocytes regulates adult neurogenesis

open access: yesCell Reports, 2023
Summary: In bacteria, archaea, protists, and plants, the hydrolysis of pyrophosphate (PPi) by inorganic pyrophosphatase (PPase) can, under stress conditions, substitute for ATP-driven proton flux to generate a proton gradient and induce luminal ...
Longze Sha   +8 more
doaj   +1 more source

Properties and Distribution of Inorganic Pyrophosphatase in Rabbit Dental Pulp

open access: yes, 1977
Some properties and the intracellular distribution of inorganic pyrophosphatase in rabbit dental pulp were determined. This enzyme was sensitive to Mg2+, and not inhibited by imidazol and CN- which are inhibitors of alkaline phosphatase.
Masae Mitsuma   +4 more
core   +1 more source

High inorganic triphosphatase activities in bacteria and mammalian cells: identification of the enzymes involved. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: We recently characterized a specific inorganic triphosphatase (PPPase) from Nitrosomonas europaea. This enzyme belongs to the CYTH superfamily of proteins.
Gregory Kohn   +10 more
doaj   +1 more source

Changes in the inorganic status and enzyme activities in senescent leaves of chickpea, Cicer arietinum L.

open access: yesActa Societatis Botanicorum Poloniae, 2014
The changes in the level of some inorganic constituents and the activities of some important enzyme systems in senescent leaves of chickpea (Cicer arietinum L.) have been studied.
Chandrashekkhar V. Murumkar   +1 more
doaj   +1 more source

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