Results 111 to 120 of about 86,294 (302)

Maintenance of Carnitine Homeostasis as a Therapeutic Strategy to Attenuate Cisplatin‐Induced Acute Kidney Injury

Food Frontiers, EarlyView.
ABSTRACT Acute kidney injury (AKI) has emerged as a significant global public health concern due to its high morbidity and mortality rates. Cisplatin, a highly effective and widely used chemotherapeutic agent, is often limited in clinical application by its nephrotoxicity, particularly AKI.
Mingkang Zhang, Yazhi Wang, Xiujuan Wang, Yan Zhou, Yanrong Ma, Xin'an Wu   +5 more
wiley   +1 more source

Codon decoding by orthogonal tRNAs interrogates the in vivo preferences of unmodified adenosine in the wobble position

Frontiers in Genetics
The in vivo codon decoding preferences of tRNAs with an authentic adenosine residue at position 34 of the anticodon, the wobble position, are largely unexplored because very few unmodified A34 tRNA genes exist across the three domains of life.
Margaret A. Schmitt, Jillyn M. Tittle, John D. Fisk   +2 more
doaj   +1 more source

Rapid, Diagnostic Test for Cardiac Ischemia [PDF]

, 2017
Current methods to detect cardiac ischemia rely on biomarkers such as troponin. Elevated levels of troponin are observed hours after the cardiac event.
Contreras, Julio, Gonzales, Jose, Nasreldeen, Abdelmagid, Physioc, Emerson, Thoresen, Evan   +4 more
core   +2 more sources

Germinant receptor diversity and germination responses of four strains of the Bacillus cereus group [PDF]

, 2010
Four strains of the Bacillus cereus group were compared for their germinant receptor composition and spore germination capacity. Phylogenetic analysis of the germinant receptor encoding operons of the enterotoxic strains B.
Abee, T., Garcia, D., Moezelaar, R., Voort, M., van der   +3 more
core   +2 more sources

A Rapid Colorimetric Method for Determining Calcium, Inorganic Phosphorus, and Zinc in Human Milk Using Clinical Laboratory Reagents

Journal of Clinical Laboratory Analysis, EarlyView.
We evaluated a colorimetric assay using clinical reagents for determining Ca, IP, and Zn in human milk. Significant correlations were observed between Ca, IP, and Zn levels determined by colorimetric assay and Ca, total P, and Zn levels determined by ICP‐AES.
Miori Tanaka, Misaki Mochida, Midori Date, Katsumi Mizuno   +3 more
wiley   +1 more source

Inhibition of inosine metabolism of the gut microbiota decreases testosterone secretion in the testis

mSystems
Growing evidence indicates that gut microbiota is involved in the regulation of the host’s sex hormone levels, such as through interfering with the sex hormone metabolism in the intestine.
Lei Tang, Xizhong Yang, Mengting Zhou, Lingxin Feng, Cuijie Ji, Jie Liang, Bei Zhang, Ruowu Shen, Luoyang Wang   +8 more
doaj   +1 more source

Making Molecules with Clay: Layered Double Hydroxides, Pentopyranose Nucleic Acids and the Origin of Life

Life, 2019
A mixture of sugar diphosphates is produced in reactions between small aldehyde phosphates catalysed by layered double hydroxide (LDH) clays under plausibly prebiotic conditions.
Harold S. Bernhardt
doaj   +1 more source

Inosine Pranobex: A Key Player in the Game Against a Wide Range of Viral Infections and Non-Infectious Diseases

Advances in Therapy, 2019
Inosine pranobex (IP), commonly known as inosine acedoben dimepranol, isoprinosine and methisoprinol, has been proven to positively impact the host’s immune system, by enhancing T-cell lymphocyte proliferation and activity of natural killer cells ...
J. Slíva, Chrysoula N. Pantzartzi, M. Votava   +2 more
semanticscholar   +1 more source

Alterations in brain metabolites in rats with experimental periodontitis: A metabolomic approach

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis (PD) is a chronic inflammatory disease with systemic effects. Emerging evidence suggests a link between periodontal inflammation and neurological changes, but the biochemical mechanisms in key brain regions, such as the hippocampus and amygdala, remain unclear.
Ramona Ramalho de Souza Pereira, Caíque Olegário Diniz e Magalhães, Elizabeth Luciana Marinho Miguel, Larissa Vieira Toledo, Débora Ribeiro Orlando, Alan Rodrigues Teixeira Machado, Bruno Del Bianco Borges, Luciano José Pereira, Marco Fabrício Dias‐Peixoto, Eric Francelino Andrade   +9 more
wiley   +1 more source

Physiological Aspects of Genetics [PDF]

, 1948
The biological sciences appear to be in the midst of a period of unprecedented progress. An important salient in the advance is the general recognition of the significance of genes in the economy of the organism.
Beadle­, G. W.
core   +2 more sources