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Inositols in Insulin Signaling and Glucose Metabolism [PDF]
, 2018 In the past decades, both the importance of inositol for human health and the complex interaction between glucose and inositol have been the subject of increasing consideration. Glucose has been shown to interfere with cellular transmembrane transport of
Bevilacqua, Arturo, Bizzarri, Mariano
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Nature Communications, 2020 The analysis of myo-inositol phosphates (InsPs) and myo-inositol pyrophosphates (PP-InsPs) is a daunting challenge due to the large number of possible isomers, the absence of a chromophore, the high charge density, the low abundance, and the instability ...
Danye Qiu +14 more
semanticscholar +1 more source
BMC Research Notes, 2018 Objective Invertebrates are productive models for understanding how inflammation, metabolism and aging are intertwined. We have deployed a dsRNA library screen to search for genes in Drosophila melanogaster—and hence identify human orthologs—that encode ...
Eui Jae Sung, Stephen B. Shears
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Current Issues in Molecular Biology, 2022 There is a problem of declining quality of rooster semen in the “native semen-equilibrium-short-term and long-term storage (cryopreservation)” cycle. The aim of this study was to determine the effects of various methods of preparing rooster semen on its ...
Yulia Silyukova +2 more
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The inositol phospholipids [PDF]
Journal of Lipid Research, 1960 T h e dried crystals melted with decomposition a t about 215”. The substance is probably an organic acid but we have not yet had time to examine it thoroughly.” (1) In this modest way inositol seems to have made its first appearance as a lipid constituent.
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Bioactivity of Inositol Phosphates [PDF]
Molecules, 2021 Inositol phosphates (IPs) are a huge and complex family of biomolecules, important in regulating vital cellular functions, signal transduction, energy transmission, and ion channels physiology and serving as structural components of cell membranes [...]
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Molecules, 2020 Inositol pyrophosphates (PP-InsPs) comprise an important group of intracellular, diffusible cellular signals that a wide range of biological processes throughout the yeast, plant, and animal kingdoms.
Stephen B. Shears, Huanchen Wang
doaj +1 more source
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase is a distant IPK member with a singular inositide binding site for axial 2-OH recognition [PDF]
, 2010 Inositol phosphates (InsPs) are signaling molecules with multiple roles in cells. In particular Graphic (InsP6) is involved in mRNA export and editing or chromatin remodeling among other events.
Agarwal +35 more
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Journal of Mid-life Health, 2018 This review describes the mechanistic, animal, and clinical data related to the use of inositols in midlife. It covers studies related to the mechanism of action of myo-inositol and D-chiro-inositol and randomized controlled trials conducted in postmenopausal women with metabolic syndrome and supports these data with the results of in vitro and animal ...
Sanjay Kalra, Bharti Kalra
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Stimulation of a glycosyl-phosphatidylinositol-specific phospholipase by insulin and the sulfonylurea, glimepiride, in rat adipocytes depends on increased glucose transport [PDF]
, 1994 . Lipoprotein lipase (LPL) and glycolipidanchored cAMP-binding ectoprotein (Gcel) are modified by glycosyl-phosphatidylinositol (GPI) in rat adipocytes, however, the linkage is potentially unstable. Incubation of the cells with either insulin (0.1-30 nM)
Bandlow, Wolfhard +3 more
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