Results 61 to 70 of about 345,398 (296)

A Solanum tuberosum inositol phosphate kinase (StITPK1) displaying inositol phosphate–inositol phosphate and inositol phosphate–ADP phosphotransferase activities [PDF]

FEBS Letters, 2008
We describe a multifunctional inositol polyphosphate kinase/phosphotransferase from Solanum tuberosum, StITPKα (GenBank accession number: EF362784), hereafter called StITPK1. StITPK1 displays inositol 3,4,5,6‐tetrakisphosphate 1‐kinase activity: K m = 27 μM, and V max = 19 nmol min−1 mg−1.
Caddick, Samuel E. K., Harrison, Christopher J., Stavridou, Ioanna, Mitchell, Jennifer L., Hemmings, Andrew M., Brearley, Charles A.   +5 more
openaire   +3 more sources

An amphitropic cAMP-binding protein in yeast mitochondria [PDF]

, 1989
: We describe the first example of a mitochondrial protein with a covalently attached phos-phatidylinositol moiety acting as a membrane anchor. The protein can be metabolically labeled with both stearic acid and inositol.
Bandlow W., Baranska J., Blok M., Brugge J., Burn P., Burn P., Cascales S. C., Cobon G. S., Cobon G. S., Cornell R., Courtneidge S. A., Cross G. A. M., Dils R. R., Dygas A., Gillfillan A. M., Guarnieri M., Hixson C. S., Hostetler K. Y., Jelsema C. L., Kraft A. S., Lassing I., Lassing I., Low M. G., Megli F. M., Meyer R. K., Muller G., Muller G., Muller G., Muller G., Nishizuka Y., Pelech S. L., Radika R., Rodel G., Rotman A., Schmidt M. F. G., Sefton B. M., Sleight R., Terce F., Towbin H., Wirtz K. W. A., Wirtz K. W. A., Wojtczak L., Yaffe M., Zborowski J.   +43 more
core   +3 more sources

Exploring Intraovarian Platelet-Rich Plasma (PRP) Therapy: A New Hope for Polycystic Ovary Syndrome (PCOS) Patients

Journal of Pharmacy and Bioallied Sciences
This case study represents a couple experiencing primary infertility for 4 years, with the male suffering from hypertension and normozoospermic condition, whereas the female suffers from Polycystic Ovary Syndrome (PCOS), which results in low ovarian ...
Aru Chaudhary, Akash More, Namrata Choudhary, Juhi Barai, Tejaswini Wadhe   +4 more
doaj   +1 more source

Down-Regulation of Inpp5e Associated With Abnormal Ciliogenesis During Embryonic Neurodevelopment Under Inositol Deficiency

Frontiers in Neurology, 2021
The inositol polyphosphate-5-phosphatase E (Inpp5e) gene is located on chromosome 9q34.3. The enzyme it encodes mainly hydrolyzes the 5-phosphate groups of phosphatidylinositol (3,4,5)-trisphosphate (PtdIns (3,4,5) P3) and phosphatidylinositol (4,5 ...
Huixuan Yue, Huixuan Yue, Shen Li, Shen Li, Jiaxing Qin, Tingting Gao, Jianjun Lyu, Yu Liu, Xiuwei Wang, Zhen Guan, Zhiqiang Zhu, Bo Niu, Rugang Zhong, Jin Guo, Jianhua Wang, Jianhua Wang   +15 more
doaj   +1 more source

Inositol and inositol 1,4,5‐trisphosphate content of Down syndrome fibroblasts exhibiting enhanced inositol uptake [PDF]

FEBS Letters, 1991
Fibroblasts from individuals with Down syndrome (DS; trisomy 21) exhibit increased inositol uptake. Here we examine the relationship between this increase in uptake and mass levels of free inositol and inositol 1,4,5‐trisphosphate (IP3) in DS fibroblasts.
Fruen, Bradley R., Lester, Bruce R.
openaire   +2 more sources

Regions of the T cell receptor alpha and beta chains that are responsible for interactions with CD3. [PDF]

, 1991
The T cell antigen receptor consists of the Ti alpha/beta heterodimer which recognizes antigen, and the associated CD3 chains, thought to be involved in signal transduction.
Tan, L, Turner, J, Weiss, A
core   +1 more source

Myo-inositol effects in women with PCOS: a meta-analysis of randomized controlled trials

Endocrine Connections, 2017
Myo-inositol (MI) supplementation in women with polycystic ovary syndrome (PCOS) has been evaluated over the last years. Many hormonal and reproductive impairments associated with this disorder seem relieved by the supplement.
Vittorio Unfer1,, Fabio Facchinetti2,, Beatrice Orrù3,, Barbara Giordani, John Nestler   +4 more
doaj   +1 more source

Inhibitors of Inositol Monophosphatase [PDF]

Journal of Enzyme Inhibition, 1999
Inositol monophosphatase (IMPase) catalyses the hydrolysis of myo-inositol monophosphates to myo-inositol, which is required in the phosphatidyl inositol cell signalling pathway. Here the enzyme structure, mechanism and inhibition of IMPase are reviewed. Lithium, an effective therapy for manic depression, is an uncompetitive inhibitor.
Fauroux, Christine M J, Freeman, Sally
openaire   +3 more sources

Harnessing 13C-labeled myo-inositol to interrogate inositol phosphate messengers by NMR† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc00151d

Chemical Science, 2019
The analysis of inositol poly- and pyrophosphates, an important group of eukaryotic messengers, is enabled by applying 13C-labeled inositol.
Robert K. Harmel, R. Puschmann, Minh Nguyen Trung, A. Saiardi, P. Schmieder, D. Fiedler   +5 more
semanticscholar   +1 more source

IRBIT a Master Regulator of Cell Physiology [PDF]

, 2017
(excerpt) Hormones and neurotransmitters regulate cell functions by binding to their receptors, which activate intracellular signaling and produce the physiological response [1].
Bouyer, Patrice G, Cook, Kelli, Petreska, Natasa   +2 more
core   +1 more source