Results 81 to 90 of about 132,246 (241)

Polycystic Ovary Syndrome: Insights into the Therapeutic Approach with Inositols

Frontiers in Pharmacology, 2017
Polycystic ovary syndrome (PCOS) is characterized by hormonal abnormalities that cause menstrual irregularity and reduce ovulation rate and fertility, associated to insulin resistance. Myo-inositol (cis-1,2,3,5-trans-4,6-cyclohexanehexol, MI) and D-chiro-
Maria A. Sortino, Salvatore Salomone, Michele O. Carruba, Filippo Drago   +3 more
doaj   +1 more source

Bridging the Gap Between Human Toxicology and Ecotoxicology Under One Health Perspective by a Cross‐Species Adverse Outcome Pathway Network for Reproductive Toxicity

Environmental Toxicology and Chemistry, EarlyView.
Cross‐species extrapolation of adverse outcome pathway network on reproductive toxicity under the One Health perspective using new approach methodologies. AOP = adverse outcome pathway. Abstract Although ecotoxicological and toxicological risk assessments are performed separately from each other, recent efforts have been made in both disciplines to ...
Elizabeth Dufourcq Sekatcheff, Jaeseong Jeong, Jinhee Choi   +2 more
wiley   +1 more source

Lithium carbonate exposure disrupts neurodevelopment by perturbing primary cilia and ER homeostasis

Ecotoxicology and Environmental Safety
Lithium, which is widely used in medicine and batteries, has become increasingly prevalent in the environment, raising concerns about its impact on human health.
Zhen Guan, Yingchao Liang, Zhiqiang Zhu, Aiyun Yang, Shen Li, Xiuwei Wang, Jianhua Wang   +6 more
doaj   +1 more source

The Tonoplastic Inositol Transporter INT1 From Arabidopsis thaliana Impacts Cell Elongation in a Sucrose-Dependent Way

Frontiers in Plant Science, 2018
The tonoplastic inositol transporter INT1 is the only known transport protein in Arabidopsis that facilitates myo-inositol import from the vacuole into the cytoplasm.
Sabrina Maria Strobl, Dominik Kischka, Ingo Heilmann, Grégory Mouille, Sabine Schneider   +4 more
doaj   +1 more source

Micro Pattern‐Based 3D Cell Culture Platform: An Overview of Technologies and Applications

Exploration, EarlyView.
Micro patterns are characterized as a coating of specific adhesion matrices on substrates to support cell growth. An overview of micropattern technology to regulate single cell morphology and fates, further focusing on the micro pattern‐based 3D cell culture platform used in the non‐tumor and tumor researches.
Xinglong Zhu, Yi Li, Hulin Long, Yijia Wu, Ningwei Sun, Shun Li, Yiyao Liu, Huiqi Xie, Ji Bao   +8 more
wiley   +1 more source

Mechanistic insights into inositol-mediated rumen function promotion and metabolic alteration using in vitro and in vivo models

Frontiers in Veterinary Science
Inositol is a bioactive factor that is widely found in nature; however, there are few studies on its use in ruminant nutrition. This study investigated the effects of different inositol doses and fermentation times on rumen fermentation and microbial ...
Guopei Yin, Zhe Sun, Zhe Sun, Zhe Sun, Zhanqing Wang, Yuanhong Xia, Long Cheng, Guixin Qin, Natnael D. Aschalew, Natnael D. Aschalew, Hongyun Liu, Xuefeng Zhang, Qilu Wu, Weigang Zhang, Wei Zhao, Tao Wang, Tao Wang, Yuguo Zhen, Yuguo Zhen   +18 more
doaj   +1 more source

Bioengineered Isoflavone–Probiotic Functional Foods for Sustainable Modulation of Metabolic and Reproductive Health in PCOS

Food Bioengineering, EarlyView.
Synergistic isoflavone‐probiotic action modulated metabolic, microbial and ovarian pathway ABSTRACT Polycystic ovary syndrome (PCOS) is a prevalent metabolic–endocrine disorder characterized by insulin resistance, hyperandrogenism, chronic inflammation, oxidative stress, and ovarian dysfunction, with growing evidence implicating gut microbiota ...
Jeyavelkumaran Renukadevi, Panneerselvam Sneha, Dhanapal Saravanan Mridula, Keerthivasan Nimithasree, Valliappan Sanjay   +4 more
wiley   +1 more source

Influence of Inositol on The Content of Oxidatively Modified Proteins and Morphological Changes in the Skin of Animals of Different Sexes with Metabolic Associated Fatty Liver Disease

Archive of Clinical Medicine
Introduction. Metabolic dysfunction-associated steatotic liver disease (MASLD) remains a leading cause of chronic liver disease worldwide. Data on the global epidemic of obesity are driving a number of obesity-related complications, including MASLD, and ...
Olesya Sopel, Olha Denefil
doaj   +1 more source

Synthetic Biology and Food: Applications and Prospects

Food Bioengineering, EarlyView.
Synthetic biology would provide revolutionary technological solutions to produce new food and feed components, such as artificial starch, animo acids, microbial protein, lipids, sweeteners, vitamins.
Yi‐Heng P. Job Zhang
wiley   +1 more source

Hyperandrogenic eumenorrheic NON-PCOS women versus women with PCOS after the GnRH-agonist stimulation test preceded by suppression of adrenal steroidogenesis with dexamethasone

Journal of Clinical & Translational Endocrinology
The subject of polycystic ovary syndrome (PCOS) has been extensively covered in the literature; however, there is a paucity of data regarding eumenorrheic women with hyperandrogenism and/or hyperandrogenemia without ultrasound evidence of PCO morphology (
Salvatore Benvenga, Michele Russo, Gianpiero Forte, Vittorio Unfer   +3 more
doaj   +1 more source