Results 81 to 90 of about 270,142 (371)

Nonlinear gap junctions enable long-distance propagation of pulsating calcium waves in astrocyte networks [PDF]

PLoS Comput Biol 6(8): e1000909, 2010
A new paradigm has recently emerged in brain science whereby communications between glial cells and neuron-glia interactions should be considered together with neurons and their networks to understand higher brain functions. In particular, astrocytes, the main type of glial cells in the cortex, have been shown to communicate with neurons and with each ...
arxiv   +1 more source

Accelerated Bone Healing via Electrical Stimulation

Advanced Science, EarlyView.
Electrical stimulation significantly impacts bone healing by enhancing osteoblast proliferation, differentiation, and vascularization through calmodulin/calcineurin/NFAT signaling. It also boosts macrophage function and cell migration, presenting a comprehensive approach to accelerating bone repair.
Jianfeng Sun, Wenqing Xie, Yuxiang Wu, Zhou Li, Yusheng Li   +4 more
wiley   +1 more source

Gestational diabetes mellitus and polycystic ovary syndrome, a position statement from EGOI-PCOS

Frontiers in Endocrinology
Gestational diabetes mellitus is a worldwide health issue in pregnancy, posing a threat to both mother and child. One of the major risk factors for the development of gestational diabetes mellitus is polycystic ovary syndrome, primarily due to the ...
Paola Quaresima, Samuel H. Myers, Basilio Pintaudi, Basilio Pintaudi, Rosario D’Anna, Rosario D’Anna, Michele Morelli, Vittorio Unfer, Vittorio Unfer   +8 more
doaj   +1 more source

Suplementação vitamínica no desenvolvimento de larvas de Jundiá (Rhamdia quelen) Vitamin suplementation on Jundiá (Rhamdia quelen) larvae development

Ciência e Agrotecnologia, 2006
Dois experimentos foram conduzidos utilizando um delineamento inteiramente casualizado, com seis tratamentos e três repetições, para avaliar o efeito de misturas vitamínicas (MV) na larvicultura do jundiá (Rhamdia quelen).
Carlos Guilherme Trombetta, João Radünz Neto, Rafael Lazzari   +2 more
doaj   +1 more source

How do new therapeutic strategies for PCOS management influence the health of the affected individuals? The narrative review

Journal of Education, Health and Sport, 2022
Introduction and purpose: Management of polycystic ovary syndrome (PCOS) is difficult since the exact pathogenic mechanism has not been established yet.
Aleksandra Wójcik, Jan Wojtas, Mikołaj Margas, Konrad Warchoł, Karol Stępniak   +4 more
doaj   +1 more source

A phenomenological cluster-based model of Ca2+ waves and oscillations for Inositol 1,4,5-trisphosphate receptor (IP3R) channels [PDF]

, 2018
Clusters of IP3 receptor channels in the membranes of the endoplasmic reticulum (ER) of many non-excitable cells release calcium ions in a cooperative manner giving rise to dynamical patterns such as Ca2+ puffs, waves, and oscillations that occur on multiple spatial and temporal scales. We introduce a minimal yet descriptive reaction-diffusion model of
arxiv   +1 more source

Regulation of store-operated calcium entry [PDF]

arXiv, 2023
Plasma membrane calcium influx through ion channels is crucial for many events in cellular physiology. Cell surface stimuli lead to the production of inositol 1,4,5-trisphosphate (IP3), which binds to IP3 receptors in the endoplasmic reticulum (ER) to release calcium pools from the ER lumen.
arxiv  

Topological Analysis of Metabolic Networks Integrating Co-Segregating Transcriptomes and Metabolomes in Type 2 Diabetic Rat Congenic Series [PDF]

, 2016
Background: The genetic regulation of metabolic phenotypes (i.e., metabotypes) in type 2 diabetes mellitus is caused by complex organ-specific cellular mechanisms contributing to impaired insulin secretion and insulin resistance.
Argoud, K, Ayala, R, Calderari, S, Cazier, JB, Collins, S, Domange, C, Dumas, ME, Gauguier, D, Gu, Q, Holmes, E, Hue, C, Lindon, JC, Mitchell, S, Navratil, V, Nicholson, JK, Otto, GW, Rodriguez Martinez, A, Suárez-Zamorano, N, Wallis, R, Wang, Y, Wilder, S   +20 more
core   +5 more sources

Anticancer Properties of Inositol Hexaphosphate and Inositol: An Overview

Journal of Nutritional Science and Vitaminology, 2019
Inositol hexaphosphate (IP6) and its parent compound myo-inositol (Ins) are active compounds from rice and other grains, with a broad spectrum of biological activities important in health and diseases. However, the most striking is the anticancer effect of IP6 and Ins that has been actively investigated during the last decades.
openaire   +4 more sources

Inositol and inositol 1,4,5‐trisphosphate content of Down syndrome fibroblasts exhibiting enhanced inositol uptake [PDF]

FEBS Letters, 1991
Fibroblasts from individuals with Down syndrome (DS; trisomy 21) exhibit increased inositol uptake. Here we examine the relationship between this increase in uptake and mass levels of free inositol and inositol 1,4,5‐trisphosphate (IP3) in DS fibroblasts.
Bruce R. Lester, Bradley R. Fruen
openaire   +3 more sources