Results 81 to 90 of about 345,398 (296)
Inositol diphosphates can transfer phosphatenonenzymatically to phosphoserine to generate diphosphate modi˜ed proteinsIP6K1 (KCS1) generated inositol diphosphatesare required for proper regulation of telomere lengthIpk2 regulates activity of Swi/Snf and Ino80chromatin-remodeling complexes in yeastIP6K1 (KCS1) is required for proper vacuole morphology ...
Hatch, Ace J., York, John D.
openaire +2 more sources
The organisation and functions of local Ca2+ signals [PDF]
Calcium (Ca2+) is a ubiquitous intracellular messenger, controlling a diverse range of cellular processes, such as gene transcription, muscle contraction and cell proliferation.
Berridge, Michael J. +2 more
core
Pertussis Toxin-sensitive Activation of Phospholipase C by the C5a and fMet-Leu-Phe Receptors [PDF]
Signal transduction pathways that mediate C5a and fMet-Leu-Phe (fMLP)-induced pertussis toxin (PTx)-sensitive activation of phospholipase C (PLC) have been investigated using a cotransfection assay system in COS-7 cells.
Jiang, Huiping +5 more
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This review describes the mechanistic, animal, and clinical data related to the use of inositols in midlife. It covers studies related to the mechanism of action of myo-inositol and D-chiro-inositol and randomized controlled trials conducted in postmenopausal women with metabolic syndrome and supports these data with the results of in vitro and animal ...
Sanjay Kalra, Bharti Kalra
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Metabotropic Glutamate Receptor Activation in Cerebelar Purkinje Cells as Substrate for Adaptive Timing of the Classicaly Conditioned Eye Blink Response [PDF]
To understand how the cerebellum adaptively times the classically conditioned nictitating membrane response (NMR), a model of the metabotropic glutamate receptor (mGluR) second messenger system in cerebellar Purkinje cells is constructed.
Bullock, Daniel +2 more
core +1 more source
The genus Parapedobacter was established to describe a novel genus within the family Sphingobacteriaceae and derives its name from Pedobacter, with which it is shown to be evolutionarily related.
Shekhar Nagar +14 more
doaj +1 more source
The Calbindin-D28k binding site on inositol monophosphatase may allow inhibition independent of the lithium site of action [PDF]
Among numerous reported biochemical effects the lithium-inhibitable enzyme inositol-monophosphatase (IMPase) remains a viable target for lithium's therapeutic mechanism of action.
Amnon Hoffman +8 more
core +1 more source
Inositol transport proteins [PDF]
The cyclic polyol myo ‐inositol is a key molecule in many different metabolic pathways among all organisms; in addition, it is fundamental for osmotic balance in the mammalian brain. This review sums up inositol transporters from eukaryotic organisms, elucidating their vital role in ...
openaire +2 more sources
Oncogenic K-Ras suppresses IP3-dependent Ca2+ release through remodeling of IP3Rs isoform composition and ER luminal Ca2+ levels in colorectal cancer cell lines [PDF]
The GTPase Ras is a molecular switch engaged downstream of G-protein coupled receptors and receptor tyrosine inases that controls multiple cell fate-determining signalling athways.
Bootman, Martin D. +4 more
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D-pinitol is a natural compound related to the important family of inositols. It can be found and isolated from many plants, being the active component of ayurvedic remedies such as Talisa patra (Abies webbiana, A.
José Ignacio López-Sánchez +2 more
doaj +1 more source

