Results 151 to 160 of about 1,279,181 (240)

Missense mutations in inositol 1,4,5-trisphosphate receptor type 3 result in leaky Ca²⁺ channels and activation of store-operated Ca²⁺ entry. [PDF]

iScience, 2022
Terry LE, Arige V, Neumann J, Wahl AM, Knebel TR, Chaffer JW, Malik S, Liston A, Humblet-Baron S, Bultynck G, Yule DI.   +10 more
europepmc   +1 more source

Effects of sulfhydryl reagents on [3H] inositol trisphosphate binding to dog cerebellar membranes

, 1989
Homogenates from dog cerebellum were fractionated using sucrose gradient centrifugation. The [3H]inositol 1,4,5-trisphosphate binding and the glucose 6-phosphatase activities were found to co-purify. The binding was saturable and had high affinity (B(max)
Yang, CM, Lee, HC
core   +1 more source

Bok binds to a largely disordered loop in the coupling domain of type 1 inositol 1,4,5-trisphosphate receptor. [PDF]

Biochem Biophys Res Commun, 2021
Szczesniak LM, Bonzerato CG, Schulman JJ, Bah A, Wojcikiewicz RJH.   +4 more
europepmc   +1 more source

Inositol 1,4,5-trisphosphate receptor type 1 autoantibody (ITPR1-IgG/anti-Sj)-associated autoimmune cerebellar ataxia, encephalitis and peripheral neuropathy: review of the literature. [PDF]

J Neuroinflammation, 2022
Jarius S, Bräuninger S, Chung HY, Geis C, Haas J, Komorowski L, Wildemann B, Roth C.   +7 more
europepmc   +1 more source

Inositol 1,4,5-trisphosphate receptor subtypes are differentially distributed between smooth muscle and endothelial layers of rat arteries

, 2004
Inositol 1,4,5-trisphosphate receptor subtypes are differentially distributed between smooth muscle and endothelial layers of rat ...
TP Murray (14449455), RE Haddock (14449452), TH Grayson (14449449), CE Hill (12148479), RJH Wojcikiewicz (14449458)   +4 more
core  

Inositol 1,4,5-trisphosphate receptor type 3 (ITPR3) is overexpressed in cholangiocarcinoma and its expression correlates with S100 calcium-binding protein A4 (S100A4). [PDF]

Biomed Pharmacother, 2022
Rodrigues MA, Gomes DA, Cosme AL, Sanches MD, Resende V, Cassali GD.   +5 more
europepmc   +1 more source

Combined Pharmacophore and Grid-Independent Molecular Descriptors (GRIND) Analysis to Probe 3D Features of Inositol 1,4,5-Trisphosphate Receptor (IP₃R) Inhibitors in Cancer. [PDF]

Int J Mol Sci, 2021
Ismatullah H, Jabeen I.
europepmc   +1 more source

Synthesis of myo-Inositol-1,4,5-trisphosphate and myo-Inositol-1,4-bisphosphate

, 1992
Racemic myo-inositol-1,4,5-trisphosphate and myo-inositol-1,4-bisphosphate, which are respectively a second messenger mobilizing Ca2+ and its physiological metabolite in the intracellular signal transduction pathway, were synthesized from myo-inositol ...
Moon, Sung-Hwan, Chung, Sung Kee, CHANG, YOUNG TAE, Ryu, Youngha   +3 more
core  

Soluble and particulate inositol 1,4,5-trisphosphate 5-phosphatases show common antigenic determinants.

, 1990
Inositol 1,4,5-trisphosphate 5-phosphatase catalyses the dephosphorylation of the phosphate in the 5-position from inositol 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate.
Verjans, Benoît, Hollande, F, Lejeune, C, Moreau, Colette, Erneux, Christophe   +4 more
core  

Formation of inositol (1,4,5) trisphosphate and increase of cytosolic Ca2+ mediated by Fc receptors in human neutrophils

, 1993
The correlation between the increase of [Ca2+]i and the activation of hydrolysis of phosphoinositide-4,5-bisphosphate and formation of inositol(1,4,5)trisphosphate in neutrophils treated with Fc receptor-binding agonists is still under discussion.
DUSI, Stefano, ROSSI, Filippo, DELLA BIANCA, Vittorina, M. Grzeskowiak   +3 more
core   +1 more source