Results 131 to 140 of about 1,279,181 (240)

SHIP1 Restrains Hypoxia/Reoxygenation‐Induced Cytokine Secretion in Mouse Bone Marrow–Derived Mast Cells

European Journal of Immunology, Volume 56, Issue 9, September 2026.
(A) BMMCs are substantially more resistant to oxygen deprivation than neurons, microglia, oligodendrocytes, astrocytes, and fibroblasts. (B) Role of SHIP‐1 in primary mouse bone marrow mast cells’ hypoxia response. Under hypoxia, SHIP‐1 induces cytokine release. SHIP1 restrains hypoxia/reoxygenation‐induced cytokine secretion in BMMCs via the RAS/ RAF,
Lara Gubeljak, Jonas Pes, Eren Arik, Aaron T. Fehr, Mara Schietinger, Thomas Wilhelm, Sandro Capellman, Michael Huber, Pardes Habib   +8 more
wiley   +1 more source

Correction: Author Correction: Tespa1 regulates T cell receptor-induced calcium signals by recruiting inositol 1,4,5-trisphosphate receptors

Nature Communications, 2018
Nature Communications 8: Article number: 15732 (2017); Published: 9 June 2017; Updated: 12 March 2018 In the original version of this Article, the affiliation details for Yan Fang were incorrectly given as “ZJU-UoE Institute, Zhejiang University School ...
Jingjing Liang, Jun Lyu, Meng Zhao, Dan Li, Mingzhu Zheng, Yan Fang, Fangzhu Zhao, Jun Lou, Chuansheng Guo, Lie Wang, Di Wang, Wanli Liu, Linrong Lu   +12 more
doaj   +1 more source

Patterns of Acute Liver Injury and Post‐Acute Liver Sequelae of COVID‐19

Liver International Communications, Volume 7, Issue 3, September 2026.
ABSTRACT Background Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is known to cause acute liver injury (ALI) in COVID‐19 patients. This study explores the association between ALI patterns and the occurrence of long‐term hepatic complications in patients with and without existing chronic liver disease (CLD).
Basile Njei, Janet Tate, Vincent Lo Re III, Joseph T. King Jr, Joseph K. Lim, Tamar Taddei, Amy C. Justice   +6 more
wiley   +1 more source

Nerve-dependent distribution of subsynaptic type 1 inositol 1,4,5-trisphosphate receptor at the neuromuscular junction. [PDF]

J Gen Physiol, 2022
Volpe P, Bosutti A, Nori A, Filadi R, Gherardi G, Trautmann G, Furlan S, Massaria G, Sciancalepore M, Megighian A, Caccin P, Bernareggi A, Salanova M, Sacchetto R, Sandonà D, Pizzo P, Lorenzon P.   +16 more
europepmc   +1 more source

Mechanisms underlying the estradiol mediated protection of yak oviduct epithelial cells against ER-Ca2+ imbalance

BMC Genomics
Background Extreme weather events are occurring with increasing frequency worldwide. Oviduct epithelial cells (OECs), which provide nutrients and a microenvironment critical for reproductive processes such as fertilization and early embryonic development,
Xiaolin Ye, Meng Wang, Yangyang Pan, Tianhao Li, Jinglei Wang, Ling Zhao, Rui Zhang, Yan Cui, Sijiu Yu   +8 more
doaj   +1 more source

Protein Posttranslational Modifications in Immunity: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 9, September 2026.
Protein posttranslational modifications, including phosphorylation, ubiquitination, SUMOylation, acetylation, methylation, glycosylation, and other new types, dynamically regulate antigen presentation and recognition, immune signal transduction, antibody production and class switching, immune contraction, immune memory establishment, as well as immune ...
Yuxing Yao, Jinxiu Qian, Qiqiong Liu, Wanting Ye, Ying Xing, Xiuyun Bai, Rongjun Deng, Jue Yang, Cheng Lu, Cheng Xiao, Yuanyan Liu   +10 more
wiley   +1 more source

Genetic Ablation of Inositol 1,4,5-Trisphosphate Receptor Type 2 (IP₃R2) Fails to Modify Disease Progression in a Mouse Model of Spinocerebellar Ataxia Type 3. [PDF]

Int J Mol Sci, 2023
Cunha-Garcia D, Monteiro-Fernandes D, Correia JS, Neves-Carvalho A, Vilaça-Ferreira AC, Guerra-Gomes S, Viana JF, Oliveira JF, Teixeira-Castro A, Maciel P, Duarte-Silva S.   +10 more
europepmc   +1 more source

The inositol 1,4,5-trisphosphate receptor in C. elegans [PDF]

, 2012
The soil nematode Caenorhabditis elegans is a genetic model organism whose cellular physiology is closely related to that of mammals, with many signaling cascades and second messengers mirroring those found in higher organisms.
†, † Baskaran Thyagarajan, Erik Allman, Keith Nehrke   +3 more
core  

DHCR24 Alleviates DNA Damage in Senescent Vascular Endothelial Cells via ENKUR/Ca2+ Signaling

Aging Cell, Volume 25, Issue 9, September 2026.
In senescent vascular endothelial cells, DHCR24 deficiency triggers ENKUR‐dependent Ca2+ overload, which in turn induces endoplasmic reticulum stress and mitochondrial dysfunction, ultimately exacerbating oxidative stress and DNA damage. ABSTRACT DNA damage is considered one of the major contributors to aging.
Han Li, Zhen Yang, Wukaiyang Liang, Jie Huang, Tianyi Ji, Hao Nie, Zixin Wan, Yuqi Qiu, Yi Huang, Le Zhang, Cuntai Zhang, Jinhua Yan   +11 more
wiley   +1 more source

Inositol 1,4,5-trisphosphate receptor type 3 is involved in resistance to apoptosis and maintenance of human hepatocellular carcinoma. [PDF]

Oncol Lett, 2022
Dos Santos ML, França A, Lima Filho ACM, Florentino RM, Diniz PH, Oliveira Lemos F, Gonçalves CAX, Coelho VL, Lima CX, Foureaux G, Nathanson MH, Vidigal PVT, Leite MF.   +12 more
europepmc   +1 more source