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Inositol 1,4,5-trisphosphate receptor type 1 autoantibodies in paraneoplastic and non-paraneoplastic peripheral neuropathy. [PDF]

open access: yesJ Neuroinflammation, 2016
Jarius S   +13 more
europepmc   +1 more source

The role of IP<sub>3</sub>R and TRPC3 channels in vasoconstriction and hypertension. [PDF]

open access: yesPflugers Arch
Moraes RDA   +4 more
europepmc   +1 more source
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Regulation of Inositol 1,4,5-Trisphosphate Receptors

Journal of Experimental Biology, 1993
ABSTRACT Inositol 1,4,5-trisphosphate [Ins(1,4,5)P3] is a soluble second messenger responsible for the generation of highly organized Ca2+ signals in a variety of cell types. These Ca2+ signals control many cellular responses, including cell growth, fertilization, smooth muscle contraction and secretion.
I C, Marshall, C W, Taylor
openaire   +2 more sources

The inositol 1,4,5-trisphosphate (InsP3) receptor

The Journal of Membrane Biology, 1995
In this review, we have described the functional properties and regulation of the InsP3R. Not all aspects of InsP3R function and regulation were covered, the main focus was on the most recent and physiologically important data. Information about the structure, heterogeneity, functional properties, and regulation of the InsP3R is useful for ...
I, Bezprozvanny, B E, Ehrlich
openaire   +2 more sources

Inositol-1,4,5-trisphosphate receptors in the vertebrate retina

Current Eye Research, 1993
Evidence has shown an activation of phosphatidylinositol 4,5-bisphosphate (PIP2) specific phospholipase C (PtdIns-PLC) by light in the vertebrate retina and rod outer segments (ROS), suggesting important roles for its two metabolites, 1,2-diacylglycerol (DG) and inositol-1,4,5-trisphosphate [Ins(1,4,5)P3].
N S, Day, C A, Koutz, R E, Anderson
openaire   +2 more sources

Inositol 1,4,5-Trisphosphate and Its Receptors

2012
Activation of cells by many extracellular agonists leads to the production of inositol 1,4,5-trisphosphate (IP₃). IP₃ is a global messenger that easily diffuses in the cytosol. Its receptor (IP₃R) is a Ca(2+)-release channel located on intracellular membranes, especially the endoplasmic reticulum (ER).
Jan B, Parys, Humbert, De Smedt
openaire   +2 more sources

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