Chlamydia trachomatis inclusion membrane protein MrcA interacts with the inositol 1,4,5-trisphosphate receptor type 3 (ITPR3) to regulate extrusion formation. [PDF]
Nguyen PH, Lutter EI, Hackstadt T.
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Inositol 1,4,5-trisphosphate receptor type 1 autoantibodies in paraneoplastic and non-paraneoplastic peripheral neuropathy. [PDF]
Jarius S +13 more
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Mitochondria‑associated endoplasmic reticulum membranes in degenerative musculoskeletal disorders: Mechanistic evidence and therapeutic perspectives (Review). [PDF]
Meng S +8 more
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The role of IP<sub>3</sub>R and TRPC3 channels in vasoconstriction and hypertension. [PDF]
Moraes RDA +4 more
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Carbonic anhydrase VIII as a regulator of intracellular calcium signaling: mechanistic insights and implications in human disease. [PDF]
Aspatwar A.
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Regulation of Inositol 1,4,5-Trisphosphate Receptors
Journal of Experimental Biology, 1993ABSTRACT Inositol 1,4,5-trisphosphate [Ins(1,4,5)P3] is a soluble second messenger responsible for the generation of highly organized Ca2+ signals in a variety of cell types. These Ca2+ signals control many cellular responses, including cell growth, fertilization, smooth muscle contraction and secretion.
I C, Marshall, C W, Taylor
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The inositol 1,4,5-trisphosphate (InsP3) receptor
The Journal of Membrane Biology, 1995In this review, we have described the functional properties and regulation of the InsP3R. Not all aspects of InsP3R function and regulation were covered, the main focus was on the most recent and physiologically important data. Information about the structure, heterogeneity, functional properties, and regulation of the InsP3R is useful for ...
I, Bezprozvanny, B E, Ehrlich
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Inositol-1,4,5-trisphosphate receptors in the vertebrate retina
Current Eye Research, 1993Evidence has shown an activation of phosphatidylinositol 4,5-bisphosphate (PIP2) specific phospholipase C (PtdIns-PLC) by light in the vertebrate retina and rod outer segments (ROS), suggesting important roles for its two metabolites, 1,2-diacylglycerol (DG) and inositol-1,4,5-trisphosphate [Ins(1,4,5)P3].
N S, Day, C A, Koutz, R E, Anderson
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Inositol 1,4,5-Trisphosphate and Its Receptors
2012Activation of cells by many extracellular agonists leads to the production of inositol 1,4,5-trisphosphate (IP₃). IP₃ is a global messenger that easily diffuses in the cytosol. Its receptor (IP₃R) is a Ca(2+)-release channel located on intracellular membranes, especially the endoplasmic reticulum (ER).
Jan B, Parys, Humbert, De Smedt
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