Results 81 to 90 of about 1,279,181 (240)
Calcium‐activated chloride channels in pericytes and their role in regulating organ blood flow
The Journal of Physiology, EarlyView.Abstract figure legend Pericytes are microvascular mural cells with diverse roles. Contractile pericytes directly regulate local perfusion, while non‐contractile pericytes coordinate upstream vascular contractility via propagating electrical signals.
Paolo Tammaro, Hikaru Hashitani
wiley +1 more source
, 2016 of Inositol 1,4,5-trisphosphate receptor type 1 autoantibodies in paraneoplastic and non-paraneoplastic peripheral ...
Klaus-Peter Wandinger (316413) +13 more
core +1 more source
A bead aggregation assay for detection of low-affinity protein-protein interactions reveals interactions between N-terminal domains of inositol 1,4,5-trisphosphate receptors. [PDF]
PLoS ONE, 2013 Interactions between proteins are a hallmark of all cellular activities. Such interactions often occur with low affinity, a feature that allows them to be rapidly reversible, but it makes them difficult to detect using conventional methods such as yeast ...
Alap P Chavda +2 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend The calcium‐activated chloride (ClCa) channel TMEM16A (also known as ANO1) plays critical roles in ion transport, neurotransmission and smooth muscle contraction. Dysregulation of TMEM16A channel activity contributes to the development and progression of various diseases.
Hisao Yamamura +4 more
wiley +1 more source
Autophosphorylation of inositol 1,4,5-trisphosphate receptors.
Journal of Biological Chemistry, 1992 Inositol 1,4,5-trisphosphate (IP3) releases internal stores of calcium by binding to a specific membrane receptor which includes both the IP3 recognition site as well as the associated calcium channel. The IP3 receptor is regulated by ATP, calcium, and phosphorylation by protein kinase A, protein kinase C, and calcium/calmodulin-dependent protein ...
C D, Ferris +4 more
openaire +2 more sources
Relationship between membrane phosphatidylinositol-4,5-bisphosphate and receptor-mediated inhibition of native neuronal M channels [PDF]
, 2005 The relationship between receptor-induced membrane phosphatidylinositol-4'5'-bisphosphate (PIP2) hydrolysis and M-current inhibition was assessed in single-dissociated rat sympathetic neurons by simultaneous or parallel recording of membrane current and ...
Abogadie, FC +6 more
core
Calmodulin and Calcium-release Channels
Biological Research, 2004 Calmodulin (CaM) is a ubiquitous cytosolic protein that plays a critical role in regulating cellular functions by altering the activity of a large number of ion channels.
NAEL NADIF KASRI +4 more
doaj
PLoS ONE, 2020 End-binding proteins (EBs) associate with the growing microtubule plus ends to regulate microtubule dynamics as well as the interaction with intracellular structures.
Hazem Abdelkarim +5 more
doaj +1 more source
Molecular genetic characterization of ataxic movement disorders in mouse and human [PDF]
, 2009 Deletion at ITPR1 underlies a young onset autosomal recessive ataxia in mice and a late onset autosomal dominant ataxia (SCA15) in humans. Data presented show the utility of investigating spontaneous mouse mutations in understanding human disease ...
van de Leemput, J.C.H. +1 more
core
Relative importance of inositol (1,4,5)trisphosphate and inositol (1,3,4,5)tetrakisphosphate in Entamoeba histolytica [PDF]
, 1996 [3H]Inositol tetrakisphosphate (Ins(1,3,4,5)P4) binding sites which were poorly displaced by unlabelled inositol (1,4,5)-trisphosphate (Ins(1,4,5)P3) were detected in membrane fractions of Entamoeba histolytica.
Biswas, Susweta +4 more
core +1 more source