Results 81 to 90 of about 2,887 (163)

Inositol hexakisphosphate (IP6) enhances the electrical excitability of Characean Nitellopsis obtusa

Plant Stress
Despite the importance of action potentials (APs) in plant stress physiology, the molecular identity of Ca2+ channels that initiate APs by passing Ca2+ into the cytoplasm is still unknown in Characean macroalgae. While the Thiel-Beilby mathematical model
Vilmantas Pupkis, Judita Janužaitė, Indrė Lapeikaitė, Vilma Kisnierienė   +3 more
doaj   +1 more source

An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor. [PDF]

Elife, 2023
Aguirre T, Dornan GL, Hostachy S, Neuenschwander M, Seyffarth C, Haucke V, Schütz A, von Kries JP, Fiedler D.   +8 more
europepmc   +1 more source

Fragment-Based Screening Identifies New Quinazolinone-Based Inositol Hexakisphosphate Kinase (IP6K) Inhibitors. [PDF]

ACS Med Chem Lett, 2023
Heitmann T, Liao G, de León P, Ernst G, Buchler I, Wei H, Shlevkov E, Brown D, Fitzek M, Collier M, Smith DM, Barrow JC.   +11 more
europepmc   +1 more source

Inositol Hexakisphosphate (InsP₆) Induces Apoptosis via Caspase-Dependent Pathways: Molecular Docking Insights

Indonesian Biomedical Journal
BACKGROUND: Inositol hexakisphosphate (InsP₆) exhibits anticancer activity, especially by inducing intrinsic and extrinsic apoptotic pathways. However, there is still no molecular docking evidence that directly examines InsP₆ interactions with either ...
Ferry Sandra, Dewi Ranggaini, Johni Halim, Alfred Pakpahan, Visi Endah Pratitis, Kyung Hoon Lee   +5 more
doaj   +1 more source

Intercalation vs Adsorption Strategies of Myo-Inositol Hexakisphosphate into Zn-Fe Layered Double Hydroxide: A Tiff between Anion Exchange and Coprecipitation. [PDF]

ACS Omega, 2023
Gogoi R, Baruah M, Borgohain A, Saikia J, Baruah VJ, Rohman S, Singh M, Kar R, Dey SK, Mazumder B, Karak T.   +10 more
europepmc   +1 more source

Kcs1 and Vip1: The Key Enzymes behind Inositol Pyrophosphate Signaling in Saccharomyces cerevisiae

Biomolecules
The inositol pyrophosphate pathway, a complex cell signaling network, plays a pivotal role in orchestrating vital cellular processes in the budding yeast, where it regulates cell cycle progression, growth, endocytosis, exocytosis, apoptosis, telomere ...
Larisa Ioana Gogianu, Lavinia Liliana Ruta, Ileana Cornelia Farcasanu   +2 more
doaj   +1 more source

The Effect of Inositol Hexakisphosphate on HIV-1 Particle Production and Infectivity can be Modulated by Mutations that Affect the Stability of the Immature Gag Lattice. [PDF]

J Mol Biol, 2023
Kleinpeter AB, Zhu Y, Mallery DL, Ablan SD, Chen L, Hardenbrook N, Saiardi A, James LC, Zhang P, Freed EO.   +9 more
europepmc   +1 more source

Inositol hexakisphosphate primes syndapin I/PACSIN 1 activation in endocytosis. [PDF]

Cell Mol Life Sci, 2022
Shi Y, Zhao K, Yang G, Yu J, Li Y, Kessels MM, Yu L, Qualmann B, Berggren PO, Yang SN.   +9 more
europepmc   +1 more source

Inositol hexakisphosphate kinases differentially regulate trafficking of vesicular glutamate transporters 1 and 2. [PDF]

Front Cell Neurosci, 2022
Li H, Datunashvili M, Reyes RC, Voglmaier SM.   +3 more
europepmc   +1 more source

Pharmacological Inhibition of Inositol Hexakisphosphate Kinase 1 Protects Mice against Obesity-Induced Bone Loss. [PDF]

Biology (Basel), 2022
Boregowda SV, Nanjappa MK, Booker CN, Strivelli J, Supper VM, Cooke PS, Phinney DG.   +6 more
europepmc   +1 more source