Bioactivity of Inositol Phosphates [PDF]
Molecules, 2021 Inositol phosphates (IPs) are a huge and complex family of biomolecules, important in regulating vital cellular functions, signal transduction, energy transmission, and ion channels physiology and serving as structural components of cell membranes [...]
Ivana Vucenik
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Role of Inositols and Inositol Phosphates in Energy Metabolism [PDF]
Molecules, 2020 Recently, inositols, especially myo-inositol and inositol hexakisphosphate, also known as phytic acid or IP6, with their biological activities received much attention for their role in multiple health beneficial effects.
Saimai Chatree +4 more
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Multiple Inositol Polyphosphate Phosphatase Compartmentalization Separates Inositol Phosphate Metabolism from Inositol Lipid Signaling [PDF]
Biomolecules, 2023 Multiple inositol polyphosphate phosphatase (MINPP1) is an enigmatic enzyme that is responsible for the metabolism of inositol hexakisphosphate (InsP6) and inositol 1,3,4,5,6 pentakisphosphate (Ins(1,3,4,5,6)P5 in mammalian cells, despite being ...
Jia Yu +6 more
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Inositol Phosphates and Retroviral Assembly: A Cellular Perspective [PDF]
Viruses, 2021 Understanding the molecular mechanisms of retroviral assembly has been a decades-long endeavor. With the recent discovery of inositol hexakisphosphate (IP6) acting as an assembly co-factor for human immunodeficiency virus (HIV), great strides have been ...
Clifton L. Ricaña, Robert A. Dick
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Overview of Inositol and Inositol Phosphates on Chemoprevention of Colitis-Induced Carcinogenesis [PDF]
Molecules, 2020 Chronic inflammation is one of the most common and well-recognized risk factors for human cancer, including colon cancer. Inflammatory bowel disease (IBD) is defined as a longstanding idiopathic chronic active inflammatory process in the colon, including
Samuel E. Weinberg +4 more
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Preliminary Investigation of Myo-Inositol Phosphates Produced by ASUIA279 Phytase on MCF-7 Cancer Cells [PDF]
International Islamic University Malaysia Engineering Journal, 2011 Phytate or myo-inositol hexakisphosphates (IP6) is widely distributed in plants like rice brans. The production of myo-inositol phosphate intermediates has received much attention due to the remarkable potential health benefits offered by the compounds ...
N. Mohd. Yusoff +7 more
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Inositol Phosphates and Synthesizing Enzymes: Implications in Neurodegenerative Disorders [PDF]
BiomoleculesInositol is a vital sugar molecule involved in numerous signaling pathways required for cellular homeostasis and cell survival. Myo-inositol and its phospho-derivatives, inositol phosphates (IPs), are the most prevalent forms of inositol found in living ...
Chisom J. Onu +4 more
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SnapShot: Inositol phosphates. [PDF]
Cell, 2010 Inositol diphosphates can transfer phosphatenonenzymatically to phosphoserine to generate diphosphate modi˜ed proteinsIP6K1 (KCS1) generated inositol diphosphatesare required for proper regulation of telomere lengthIpk2 regulates activity of Swi/Snf and Ino80chromatin-remodeling complexes in yeastIP6K1 (KCS1) is required for proper vacuole morphology ...
Hatch AJ, York JD.
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Effect of Phytate (InsP6) and Other Inositol-Phosphates (InsP5, InsP4, InsP3, InsP2) on Crystallization of Calcium Oxalate, Brushite, and Hydroxyapatite [PDF]
Biomolecules, 2023 Pathological calcifications may consist of calcium oxalate (CaOx), hydroxyapatite (HAP), and brushite (BRU). The objective of this study was to evaluate the effect of phytate (inositol hexakisphosphate, InsP6), InsP6 hydrolysates, and individual lower ...
Paula Calvó +2 more
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Inositol Phosphates Purification Using Titanium Dioxide Beads [PDF]
Bio-Protocol, 2018 Inositol phosphates (IPs) comprise a family of ubiquitous eukaryotic signaling molecules. They have been linked to the regulation of a pleiotropy of important cellular activities, but low abundance and detection difficulties have hampered our ...
Miranda Wilson, Adolfo Saiardi
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