A sensitive method to directly measure the mass of inositol phosphates from biologic samples is described. The procedure uses ammonium sulfate gradient elution anion exchange column chromatography to isolate inositol monophosphate, bisphosphate ...
SD DaTorre, PB Corr, MH Creer
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A Role for Phosphoinositides in Regulating Plant Nuclear Functions
Nuclear localized inositol phospholipids and inositol phosphates are important for regulating many essential processes in animal cells such as DNA replication, recombination, RNA processing, mRNA export and cell cycle progression.
Catherine B Dieck +2 more
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Background. Myo-inositol has emerged as one of the preventive therapies for the development of gestational diabetes mellitus in at-risk populations.
Patricia Ann Factor, Hannah Corpuz
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Certain Malvaceae Plants Have a Unique Accumulation of myo-Inositol 1,2,4,5,6-Pentakisphosphate
Methods used to quantify inositol phosphates in seeds lack the sensitivity and specificity necessary to accurately detect the lower concentrations of these compounds contained in the leaves of many plants.
Brian Q. Phillippy +3 more
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A novel method for the purification of inositol phosphates from biological samples reveals that no phytate is present in human plasma or urine [PDF]
Inositol phosphates are a large and diverse family of signalling molecules. While genetic studies have discovered important functions for them, the biochemistry behind these roles is often not fully characterized.
Miranda S. C. Wilson +4 more
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Identification and characterization of insulin-like growth factor receptors on adult rat cardiac myocytes: linkage to inositol 1,4,5-trisphosphate formation. [PDF]
Cultured cardiac myocytes from adult Sprague-Dawley rats express both insulin-like growth factor-I (IGF-I) receptors and insulin-like growth factor-II/mannose 6-phosphate (IGF-II/Man6P) receptors and respond to IGF-I with a dose-dependent accumulation of
Berg, Ingeborg +6 more
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Lactic acid and thermal treatments trigger the hydrolysis of myo-inositol hexakisphosphate and modify the abundance of lower myo-inositol phosphates in barley (Hordeum vulgare L.). [PDF]
Barley is an important source of dietary minerals, but it also contains myo-inositol hexakisphosphate (InsP6) that lowers their absorption. This study evaluated the effects of increasing concentrations (0.5, 1, and 5%, vol/vol) of lactic acid (LA ...
Barbara U Metzler-Zebeli +4 more
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Inositol pyrophosphates and their unique metabolic complexity: analysis by gel electrophoresis.
Inositol pyrophosphates are a recently characterized cell signalling molecules responsible for the pyrophosphorylation of protein substrates. Though likely involved in a wide range of cellular functions, the study of inositol pyrophosphates has suffered ...
Szijgyarto Zsolt +11 more
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Inositol metabolism as a broad-spectrum antiviral target
Inositol plays many important roles in cellular processes through its various derivatives including phosphatidylinositol phosphates. Viruses use phosphatidylinositol phosphates for their replication in multiple processes including entry, formation of ...
Kunlakanya Jitobaom +3 more
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HPLC Separation of Inositol Polyphosphates
High performance liquid chromatography (H PLC) is an essential analytical tool in the study of the large number of inositol phosphate isomers. This chapter focuses on the separation of inositol polyphosphates from [H-3]myo-inositol labeled tissues and ...
Barker, Christopher J. +8 more
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