Insights into the activation mechanism of class I HDAC complexes by inositol phosphates [PDF]
Nature Communications, 2016 Class I histone deacetylase complexes can be activated by inositol phosphates. Here, the authors investigate the stereochemical requirements for activation; use the crystal structure to understand substrate recognition, and suggest an entropically driven
Peter J. Watson +9 more
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Binding of inositol phosphates to arrestin [PDF]
FEBS Letters, 1991 Arrestin binds to phosphorylated rhodopsin in its light-activated form (metarhodopsin II), blocking thereby its interaction with the G-protein, transducin.
Pulvermüller, Alexander +4 more
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Preliminary Investigation of Myo-Inositol Phosphates Produced by ASUIA279 Phytase on MCF-7 Cancer Cells [PDF]
International Islamic University Malaysia Engineering Journal, 2011 Phytate or myo-inositol hexakisphosphates (IP6) is widely distributed in plants like rice brans. The production of myo-inositol phosphate intermediates has received much attention due to the remarkable potential health benefits offered by the compounds ...
N. Mohd. Yusoff +7 more
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The intracellular inositol (pyro)phosphate receptor AtSPX1 reciprocally binds to P1BS DNA [PDF]
Nature CommunicationsThe response of plants to phosphate starvation engages PHR (CC-MYB-PHOSPHATE STARVATION RESPONSE) transcription factors that bind to P1BS (GNATATNC) promoter elements of phosphate-starvation induced (PSI) genes. The encoded proteins include single-domain
Hayley L. Whitfield +6 more
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Protein pyrophosphorylation by inositol phosphates: a novel post-translational modification in plants? [PDF]
Frontiers in Plant ScienceInositol pyrophosphates (PP-InsPs) are energy-rich molecules harboring one or more diphosphate moieties. PP-InsPs are found in all eukaryotes evaluated and their functional versatility is reflected in the various cellular events in which they take part ...
Yeshambel Emewodih Mihiret +2 more
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Metabolism of inositol derivatives by the gut microbiome [PDF]
Gut MicrobesThe gut microbiome harbors immense metabolic capacity, much of which is still being uncovered. Recent discoveries have highlighted the ability of gut microbes to metabolize inositol-derived compounds, including free inositols and their phosphorylated ...
Henning Jessen, Thi Phuong Nam Bui
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Inositol phosphates and their metabolism in plants.
, 1996 The discovery that plasma membrane phosphoinositides mediate cellular responses to external signals has led to tremendous interest in the structure and metabolism of phosphoinositides and inositol phosphates.
Pushpalatha P. N. Murthy, Murthy, P. P.
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Mass measurement of inositol phosphates
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1989 This review summarises the methods available for the mass measurement of inositol phosphates, i.e., use of radioactive inositol lipid precursors, optical techniques, gas chromatography, mass spectrometry, nuclear magnetic resonance, fast atom bombardment
Palmer, S, Wakelam, M J
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Phytate (Inositol Hexakisphosphate) in Soil and Phosphate Acquisition from Inositol Phosphates by Higher Plants. A Review [PDF]
Plants, 2015 Phosphate (P) fixation to the soil solid phase is considered to be important for P availability and is often attributed to the strong binding of orthophosphate anion species.
Jörg Gerke
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Phytase dose-dependent response of kidney inositol phosphate levels in poultry.
PLoS ONE, 2022 Phytases, enzymes that degrade phytate present in feedstuffs, are widely added to the diets of monogastric animals. Many studies have correlated phytase addition with improved animal productivity and a subset of these have sought to correlate animal ...
Colleen Sprigg +5 more
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