Binding of inositol phosphates to arrestin [PDF]
Arrestin binds to phosphorylated rhodopsin in its light‐activated form (metarhodopsin II), blocking thereby its interaction with the G‐protein, transducin. In this study, we show that highly phosphorylated forms of inositol compete against the arrestin‐rhodopsin interaction.
Palczewski, Krzysztof +4 more
openaire +4 more sources
Towards Improved Bioavailability of Cereal Inositol Phosphates, Myo-Inositol and Phenolic Acids [PDF]
Cereals are among the foods rich in myo-inositol hexakisphosphate (phytic acid, IP6), lower myo-inositol phosphates (IPx), a wide range of phenolic compounds, as well as vitamins, minerals, oligosaccharides, phytosterols and para-aminobenzoic acid, and ...
Krzysztof Żyła, Aleksandra Duda
doaj +2 more sources
Inhibition of vascular calcification by inositol phosphates derivatized with ethylene glycol oligomers [PDF]
Cardiovascular calcification is a serious pathology for which effective pharmacological treatments are lacking. Here the authors show that an optimized oligo(ethylene glycol) derivative of inositol phosphate interferes with calcium phosphate ...
Antonia E. Schantl +21 more
doaj +2 more sources
Insights into the activation mechanism of class I HDAC complexes by inositol phosphates [PDF]
Class I histone deacetylase complexes can be activated by inositol phosphates. Here, the authors investigate the stereochemical requirements for activation; use the crystal structure to understand substrate recognition, and suggest an entropically driven
Peter J. Watson +9 more
doaj +2 more sources
Protein pyrophosphorylation by inositol phosphates: a novel post-translational modification in plants? [PDF]
Inositol pyrophosphates (PP-InsPs) are energy-rich molecules harboring one or more diphosphate moieties. PP-InsPs are found in all eukaryotes evaluated and their functional versatility is reflected in the various cellular events in which they take part ...
Yeshambel Emewodih Mihiret +2 more
doaj +2 more sources
The intracellular inositol (pyro)phosphate receptor AtSPX1 reciprocally binds to P1BS DNA [PDF]
The response of plants to phosphate starvation engages PHR (CC-MYB-PHOSPHATE STARVATION RESPONSE) transcription factors that bind to P1BS (GNATATNC) promoter elements of phosphate-starvation induced (PSI) genes. The encoded proteins include single-domain
Hayley L. Whitfield +6 more
doaj +2 more sources
Pho84/GLUT2 are cellular myo-inositol exporters regulated by inositol pyrophosphates [PDF]
Inositol is an essential nutrient for most living organisms, as combinatorial phosphorylation on this cyclic sugar generates key cellular messengers, such as lipid-bound phosphoinositides (PtdInsPs), water-soluble inositol phosphates (InsPs), and high ...
Xue Bessie Su +6 more
doaj +2 more sources
Phytase dose-dependent response of kidney inositol phosphate levels in poultry.
Phytases, enzymes that degrade phytate present in feedstuffs, are widely added to the diets of monogastric animals. Many studies have correlated phytase addition with improved animal productivity and a subset of these have sought to correlate animal ...
Colleen Sprigg +5 more
doaj +2 more sources
Inert digestibility index markers such as titanium dioxide are universally accepted to provide simple measurement of digestive tract retention and relative digestibility in poultry feeding trials.
Colleen Sprigg +5 more
doaj +3 more sources
Inositol phosphates as an overlooked phosphorous source in marine ecosystems. [PDF]
Inositol phosphates, common phosphorus storage compounds that are also crucial for eukaryotic cell signaling, constitute a significant portion of dissolved organic phosphorus in coastal waters.
Teng ZJ +6 more
europepmc +2 more sources

