Results 51 to 60 of about 828,541 (175)

Biosynthesis and possible functions of inositol pyrophosphates in plants

Frontiers in Plant Science, 2015
Inositol phosphates (InsPs) are intricately tied to lipid signaling, as at least one portion of the inositol phosphate signaling pool is derived from hydrolysis of the lipid precursor, phosphatidyl inositol (4,5) bisphosphate. The focus of this review is
Sarah Phoebe Williams, Glenda E Gillaspy, Imara Yasmin Perera   +2 more
doaj   +1 more source

Generation of inositol polyphosphates through a phospholipase C-independent pathway involving carbohydrate and sphingolipid metabolism in Trypanosoma cruzi

mBio
Inositol phosphates are involved in a myriad of biological roles and activities such as Ca2+ signaling, phosphate homeostasis, energy metabolism, and disease pathogenicity.
Mayara S. Bertolini, Sabrina E. Cline, Miguel A. Chiurillo, Brian S. Mantilla, Aharon Eidex, Logan P. Crowe, Danye Qiu, Henning J. Jessen, Adolfo Saiardi, Roberto Docampo   +9 more
doaj   +1 more source

ROLES OF INOSITOL PHOSPHATES AND INOSITOL PYROPHOSPHATES IN DEVELOPMENT, CELL SIGNALING AND NUCLEAR PROCESSES

Advances in Enzyme Regulation, 2009
Inositol phosphates and inositol pyrophosphates are small molecule metabolites that play important roles in nuclear processes such as transcription control, mRNA export and DNA repair.
M. M. Tsui, J. York
semanticscholar   +1 more source

Simultaneous HPLC determination of soluble signaling molecules and metabolic status in neuroblastoma cell cultures

Physiological Reports
Several laboratories have explored the capacity of the anion exchange chromatography method in evaluating distinct forms of inositol phosphates in a single analytical process.
Natalie Chaves Ferreira, Chiara Gatnau‐Civardi, Miquel Riera‐Codina   +2 more
doaj   +1 more source

Beyond phytic acid: Nutrigenetic and nutrigenomic insights into its hydrolysis, transport, and metabolism

Journal of Agriculture and Food Research
Phytic acid (inositol hexakisphosphate, IP6), often known as an antinutrient for its mineral-chelating properties, has emerged as a precursor to bioactive metabolites with significant health roles.
Suyun Choi, Sangyong Choi
doaj   +1 more source

Signalling Properties of Inositol Polyphosphates

Molecules, 2020
Several studies have identified specific signalling functions for inositol polyphosphates (IPs) in different cell types and have led to the accumulation of new information regarding their cellular roles as well as new insights into their cellular ...
Tania Maffucci, Marco Falasca
doaj   +1 more source

Characterization of the Inositol Monophosphatase Gene Family in Arabidopsis

Frontiers in Plant Science, 2015
Synthesis of myo-inositol is crucial in multicellular eukaryotes for production of phosphatidylinositol and inositol phosphate signaling molecules. The myo-inositol monophosphatase (IMP) enzyme is required for the synthesis of myo-inositol, breakdown of
Aida eNourbakhsh, Eva eCollakova, Glenda E Gillaspy   +2 more
doaj   +1 more source

High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity*

Journal of Biological Chemistry, 1997
The influence of inositol phosphates and phosphoinositides on the α isoform of the RAC-protein kinase B (RAC/PKB) was studied using purified wild type and mutant kinase preparations and a recombinant pleckstrin homology (PH) domain.
M. Frech, M. Andjelkovic, E. Ingley, K. Reddy, J. Falck, B. Hemmings   +5 more
semanticscholar   +1 more source

Synthetic Pores as Sensors: Focus on Zinc Filters for IP7 and Phytate Contents in Lentils, Almonds, and Soybeans

CHIMIA, 2008
Recent experimental evidence confirms synthetic pores as operational multicomponent sensors in complex matrices. This work in practice is summarized, with emphasis on topics of current concern which exemplify the use of enzymes as signal ...
Sara M. Butterfield, Stefan Matile
doaj   +1 more source

Heteromeric, but Not Homomeric, Connexin Channels Are Selectively Permeable to Inositol Phosphates*

Journal of Biological Chemistry, 2006
Previous work has shown that channels formed by both connexin (Cx)26 and Cx32 (heteromeric Cx26/Cx32 hemichannels) are selectively permeable to cAMP and cGMP.
Wafaa A. Ayad, Darren Locke, Irina V. Koreen, A. Harris   +3 more
semanticscholar   +1 more source