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Cell Signalling by Inositol Pyrophosphates

2012
Inositol serves as a module for the generation of a high level of molecular diversity through the combinatorial attachment and removal of phosphate groups. The array of potential inositol-containing molecules is further expanded by the generation of diphospho inositol polyphosphates, commonly referred as inositol pyrophosphates.
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Influence of Inositol Pyrophosphates on Cellular Energy Dynamics

Science, 2011
Inositol pyrophosphates are implicated in coordination of cell proliferation and metabolism.
Zsolt, Szijgyarto   +3 more
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A Discrete Signaling Function for an Inositol Pyrophosphate

Science's STKE, 2007
Inositol pyrophosphates were, until recently, without clearly defined functions. Two recent papers in Science have now clearly defined a function for an IP 7 pyrophosphate (inositol hexaphosphate with one pyrophosphate) that is the product of the enzyme encoded by the Vip1
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Understanding the biological significance of diphosphoinositol polyphosphates (‘inositol pyrophosphates’)

Biochemical Society Symposia, 2007
Among the many derivatives of the inositol-based signalling family are a subgroup that possess diphosphates. In this review, some recent research into the actions of these specialized polyphosphates is analysed, and key goals for future studies are identified, which, it is hoped, will result in the wider cell-signalling community giving considerably ...
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Inositol pyrophosphate kinases in health and disease

FEBS Letters
Inositol phosphates (InsPs) are intracellular signaling molecules that are essential for life. Inositol pyrophosphates, a subset of inositol phosphates, are the end products of inositol phosphate metabolism. In mammalian cells, up to 90% of inositol pyrophosphates are 5‐diphosphoinositol 1,2,3,4,6‐pentakisphosphate (5PP‐InsP
Changchang Xing   +6 more
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Triplexed Affinity Reagents to Sample the Mammalian Inositol Pyrophosphate Interactome

Cell Chemical Biology, 2020
David Furkert   +2 more
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Signals | The Inositol Pyrophosphate Signaling Family

2021
Soumyadip Sahu, Stephen B. Shears
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Inositol Pyrophosphate InsP8 Acts as an Intracellular Phosphate Signal in Arabidopsis

Molecular Plant, 2019
Jinsong Dong   +2 more
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