Results 141 to 150 of about 22,690,992 (295)
Вестник Пермского государственного гуманитарно-педагогического университета. Серия № 1. Психологические и педагогические науки, 2014 Статья анализирует три подхода к обучению языкам (модели применимы к другим дисциплинам). Первый подход знаниево-ориентированный предполагает заучивание лексики и репродуцирование материала, трансляцию материала в фактическом виде, предъявление в готовом виде синтаксических конструкций и грамматических правил, их отработку в упражнениях, оценивание ...
openaire +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Inquiry-based learning: A pedagogical tool to improving understanding of natural hazards. [PDF]
Jamba, 2022 Aksa FI.
europepmc +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
An Inquiry-Based Learning STEM Outreach Module to Teach Principles of Bioadhesives and Tissue Repair. [PDF]
Annu Conf Expo (Am Soc Eng Educ), 2023 Panebianco MCJ +7 more
europepmc +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Increase in institutional delivery and child immunisation coverage through an appreciative inquiry-based community dialogue intervention in Afghanistan. [PDF]
Public Health Pract (Oxf), 2023 Hemat S, Alemi S, Ahmady S, Nakamura K.
europepmc +1 more source
Commission on Evidence-Based Policymaking
, 2017 Website for the Commission on Evidence-Based Policymaking (CEP), which was established to create a strategy for increasing access to data about government programs while protecting confidentiality. It includes hearings, meeting minutes, and news as well
United States. Commission on Evidence-Based Policymaking.
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source