Results 151 to 160 of about 22,690,992 (295)

Teaching Tissue Repair Through an Inquiry-Based Learning Bioadhesives Module. [PDF]

open access: yesBiomed Eng Educ, 2023
Panebianco CJ   +7 more
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Why Ones Practical Reasons Are Not Just Ones Own Private Affair

open access: yes, 2017
Stefano Bertea, Philosophical Inquiry
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Online Orbital Explorer and BingOrbital Game for Inquiry-Based Activities. [PDF]

open access: yesJ Chem Educ, 2022
Li X   +5 more
europepmc   +1 more source

The effectiveness of inquiry-based learning by scaffolding students to ask “5 why” questions

open access: yes, 2014
[[abstract]]This study aims to research on the effectiveness of inquiry-based learning from Scaffolding theory by self-made bread course. The Inquiry-based learning puts more emphasis on scaffolding learners to ask “5 Why” questions step by step during
Lu, C. C;Hong, J. C;Tseng Y. C.
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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