Results 171 to 180 of about 28,669,668 (285)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

A Probe into the Efficacy of Teacher-led vs. Student-directed Inquiry-based Approach for Iranian EFL Learners' Expository Writing Betterment

open access: yesResearch in English Language Pedagogy
Though not a newfangled avenue of research in applied linguistics, inquiry-based learning (IBL) has witnessed a renewed outgrowth of research addressing its unexplored perspectives in recent years.
Masoud Shahkarami, Parviz Alavini
doaj  

Using mobile devices to enhance inquiry-based learning processes

open access: yes, 2020
Sebastian Becker   +3 more
semanticscholar   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Understanding teacher design practices for digital inquiry-based science learning: the case of Go-Lab. [PDF]

open access: yesEduc Technol Res Dev, 2021
de Jong T   +13 more
europepmc   +1 more source

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