Results 181 to 190 of about 16,142,007 (311)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Impact of guided inquiry-based laboratory experiments on secondary school students' attitudes toward biology in Ethiopia: A quasi-experimental study. [PDF]

PLoS One
Chengere AM, Bono BD, Zinabu SA, Jilo KW.   +3 more
europepmc   +1 more source

Integrating Bioinformatics Tools Into Inquiry-Based Molecular Biology Laboratory Education Modules. [PDF]

Front Educ (Lausanne), 2021
Goller CC, Srougi MC, Chen SH, Schenkman LR, Kelly RM.   +4 more
europepmc   +1 more source

Developing a continuous professional development to enhance inquiry-based science teaching

, 2014
In this paper, based on PROFILES, a continuous professional development (CPD) program developed in Karlstad Sweden is presented. A main strategy was to incorporate the elements of (1) the existing laboratory teaching tradition and (2) the teachers’ group
Chang Rundgren, Shu-Nu,, Lunde, Torodd,
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Critical Analysis of Preprints and Inquiry-Based Lessons Improve the Synthetic Biology Learning Experience. [PDF]

ACS Synth Biol
Nevot G, Güell M, Santos-Moreno J.
europepmc   +1 more source

Computer-assisted instruction versus inquiry-based learning: The importance of working memory capacity. [PDF]

PLoS One, 2021
Chevalère J, Cazenave L, Berthon M, Martinez R, Mazenod V, Borion MC, Pailler D, Rocher N, Cadet R, Lenne C, Maïonchi-Pino N, Huguet P.   +11 more
europepmc   +1 more source

Expert Report for the UK Covid-19 Public Inquiry: Module 2B: Welsh Government core political and administrative decision-making in relation to the Covid-19 pandemic [PDF]

Expect Report for the UK Covid-19 Public Inquiry: Module 2B: Welsh Government core political and administrative decision-making in relation to the Covid-19 ...
Wincott, Daniel, UK Covid-19 Public Inquiry   +1 more
core  

Inquiry-based science [PDF]

, 2021
openaire   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source