Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Critical Analysis of Preprints and Inquiry-Based Lessons Improve the Synthetic Biology Learning Experience. [PDF]
Nevot G, Güell M, Santos-Moreno J.
europepmc +1 more source
Integrating Bioinformatics Tools Into Inquiry-Based Molecular Biology Laboratory Education Modules. [PDF]
Goller CC +4 more
europepmc +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
The efficacy of an inquiry-based stress reduction program on self-compassion and compassion for others in undergraduate nursing students. [PDF]
Jamali M +3 more
europepmc +1 more source
An Inquiry-Based Teaching Model for Nursing Professional Courses Based on Data Mining and Few-Shot Learning Technology. [PDF]
Fan F.
europepmc +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Enhancing secondary school students' science process skills through guided inquiry-based laboratory activities in biology. [PDF]
Chengere AM +3 more
europepmc +1 more source
Computer-assisted instruction versus inquiry-based learning: The importance of working memory capacity. [PDF]
Chevalère J +11 more
europepmc +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source

