Results 111 to 120 of about 59,060 (257)

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Inquiry based learning

open access: yesВестник Пермского государственного гуманитарно-педагогического университета. Серия № 1. Психологические и педагогические науки, 2014
Статья анализирует три подхода к обучению языкам (модели применимы к другим дисциплинам). Первый подход знаниево-ориентированный предполагает заучивание лексики и репродуцирование материала, трансляцию материала в фактическом виде, предъявление в готовом виде синтаксических конструкций и грамматических правил, их отработку в упражнениях, оценивание ...
openaire   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang   +4 more
wiley   +1 more source

Utilising educational technologies to support inquiry-based learning in natural science

open access: yesInternational Journal of Educational Management and Development Studies
The study explored the technologies that can be used to support Inquiry-Based Learning (IBL) in Natural Science (NS) in Ekurhuleni schools, Gauteng.
Benkosi Madlela, Ramnarain Umesh
doaj   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi   +17 more
wiley   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian   +8 more
wiley   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs   +7 more
wiley   +1 more source

Inquiry-Based Knowledge Transformation: A Comparative Case of Two Secondary School Biology Teachers’ Involvement in an Extended Professional Learning Community Program

open access: yesEducation Sciences
This article presents a qualitative case study of two secondary school biology teachers who aligned their teaching to inquiry through an extended professional learning community (PLC) program. The case study used an inquiry-based knowledge mobility model
Joy Anogwih   +2 more
doaj   +1 more source

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