Results 51 to 60 of about 1,022,390 (280)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Promoting Inquiry in Science Classrooms in European Schools : a Handbook for Tutors [PDF]

, 2011
In Scotland, PISCES stands for Promoting Inquiry Skills for a Curriculum for Excellence in Science. It is a CPD module for teachers of science, which has been developed in Scotland with the support of the S-TEAM project.
Blake, Allan, Gray, Peter, Kelly, Fearghal, Mcnally, James, Smith, Colin   +4 more
core  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Design for Inquiry-based Learning Case Studies

Journal of Learning Development in Higher Education, 2009
The past six months have witnessed the development and dissemination of a number of case studies of inquiry-based learning (IBL) projects supported and developed by the Centre for Inquiry-based Learning in the Arts and Social Sciences (CILASS), a Centre ...
Jamie Peter Wood
doaj   +1 more source

Inquiry-Based Learning on the Cloud [PDF]

, 2016
Cloud Learning Environments (CLEs) have recently emerged as a novel approach to learning, putting learners in the spotlight and providing them with the cloud-based tools for building their own learning environments according to their specific learning needs and aspirations.
Mikroyannidis, Alexander, Okada, Alexandra, Correa, Andre, Scott, Peter   +3 more
openaire   +3 more sources

Pengembangan Model Pembelajaran Inkuiri Kolaboratif Berbasis Potensi Lokal Dan Implementasinya Pada Materi Tumbuhan Lumut Dan Paku [PDF]

, 2017
Learning will be more interesting and meaningful when using models and appropriate learning tools that fit with the character of the learning material being studied.
Langgeng, L. (Langgeng), Prayitno, B. A. (Baskoro), Sajidan, S. (Sajidan)   +2 more
core  

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

How Does Leadership Matter? Developing and Teaching a Definition of Hands-On Science, a Prerequisite for Effective Inquiry Teaching [PDF]

, 2013
This descriptive case study describes leadership skills and planning for setting clear directions by program leaders for a statewide professional development initiative to extend improvement in science teaching and learning.
Sterling, D. R.
core   +1 more source

Building Forts and Drawing on Walls: Fostering Student-Initiated Creativity Inside and Outside the Elementary Classroom [PDF]

, 2012
The arts embody one of the oldest forms of knowledge and knowing and action research provides opportunities to experiment with art as an integral part of the creation and dissemination of knowledge.This report is a personal account of a teacher with 16 ...
David Rufo
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source