Results 41 to 50 of about 127,707 (312)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Investigating Inquiry Pedagogy: Cracking The Code of Learning
, 2015 Embracing a humanistic view, it is recognised that students have a natural desire for learning and educators have a similar desire to provide an environment that facilitates this learning to enhance student potential.
McLennan, Brad +3 more
core +1 more source
Learning and Teaching in Early Childhood: Pedagogies of Inquiry and Relationships
, 2021 Learning and Teaching in Early Childhood: Pedagogies of Inquiry and Relationships is an introduction for early childhood educators beginning their studies.
Green, Nicole C. +2 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Jurnal Pendidikan IPA Indonesia, 2017 This research was conducted to (1) produce science material learning based Authentic Inquiry Learning which is appropriate to improve problem solving and students scientific attitude; (2) know the potency of developing scientific attitude in science ...
A. Widowati, S. Nurohman, P. Anjarsari
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Education SciencesOpen Educational Resources (OER) have emerged as a cost-effective alternative to traditional commercial textbooks in higher education, towards the goal of alleviating college students’ financial burden of educational expenses.
Hengtao Tang, Yan Yang, Yu Bao
doaj +1 more source
PENERAPAN METODE INQUIRY PADA MATERI HIMPUNAN
Jurnal E-DuMath, 2016 This study aims to find the average of student learning achievement by implementing inquiry and expository method on sets material. To determine the difference between mathematics students learning achievement in the class that used inquiry method and ...
Ana Istiani
doaj +1 more source
Inquiry in University Mathematics Teaching and Learning
, 2021 The book presents developmental outcomes from an EU Erasmus+ project involving eight partner universities in seven countries in Europe. Its focus is the development of mathematics teaching and learning at university level to enhance the learning of ...
Heck, André +31 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source