Results 121 to 130 of about 868,028 (301)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Collaborative Inquiry For 4C Skills [PDF]

open access: yesProceedings of the 3rd Annual International Seminar on Transformative Education and Educational Leadership (AISTEEL 2018), 2018
Wawan Bunawan   +2 more
openaire   +1 more source

Investigating Scientific Inquiry Skills from Process Data

open access: yes, 2021
Process data recording students’ interactions with digital assessment items are available in digital educational assessments and have become a focus of cognitive scientists to analyze inquiry skills during problem solving. This study examines the inquiry behaviors of using tools (i.e., resource tabs) in short response construction items from the 2019 ...
Gong, Tao, Jiang, Yang, Arslan, Burcu
openaire   +1 more source

Computational Thinking Integration into Middle Grades Science Classrooms: Strategies for Meeting the Challenges [PDF]

open access: yes, 2018
This paper reports findings from the efforts of a university-based research team as they worked with middle school educators within formal school structures to infuse computer science principles and computational thinking practices.
Akram, Bita   +7 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Study of effect of argument driven inquiry model and mathematical literacy on student mathematical communication

open access: yesAl-Jabar
Background: Mathematical communication skills are an important aspect of mathematics learning that allows students to explore and consolidate their mathematical thinking clearly and precisely. Aim: This study aims to analyze the effect of Argument Driven
Riyama Ambarwati   +5 more
doaj   +1 more source

Valuing Critical Inquiry Skills in Museum Literacy

open access: yesSocial Studies Research and Practice, 2016
As content acquisition is often conceived of as the primary goal of a museum visit, advice for social studies teachers on making the most of field trips primarily focuses on ways to increase the information absorbed by students. Yet, research in museum studies provides ample evidence for questioning this underlying assumption.
openaire   +1 more source

Amazing Space: The Helix Nebula - NGC 7293 Lithograph [PDF]

open access: yes, 2003
This lithograph features Hubble Space Telescope images and includes text that describes and explains the images. The images provide motivation for students to explore and formulate questions.

core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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