Results 51 to 60 of about 773,035 (293)
Insertion variants missing in the human reference genome are widespread among human populations
BMC Biology, 2020 Background Structural variants comprise diverse genomic arrangements including deletions, insertions, inversions, and translocations, which can generally be detected in humans through sequence comparison to the reference genome. Among structural variants,
Young-gun Lee +3 more
doaj +1 more source
To Be or Not to Be Mesophilic, That Is the Question for Aeromonas salmonicida
Microorganisms, 2022 The bacterium Aeromonas salmonicida has long been known to be one of the most feared pathogens in fish farming. However, the more we discover about this bacterial species, the more we question whether it is really exclusively an aquatic pathogen.
Antony T. Vincent, Steve J. Charette
doaj +1 more source
A q-weighted version of the Robinson-Schensted algorithm
, 2013 We introduce a q-weighted version of the Robinson-Schensted (column insertion) algorithm which is closely connected to q-Whittaker functions (or Macdonald polynomials with t=0) and reduces to the usual Robinson-Schensted algorithm when q=0.
O'Connell, Neil, Pei, Yuchen
core +1 more source
The regions of the herpes simplex virus type 1 immediate early protein Vmwl75 required for site specific DNA binding closely correspond to those involved in transcriptional regulation [PDF]
, 1988 The immediate-early (IE) protein Vmw175 (ICP4) of HSV-1 is required for the transcription of later classes of viral genes and the repression of IE gene expression.
Everett, R.D., Paterson, T.
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Journal of Infection and Public Health, 2020 Objectives: Acinetobacter baumannii emerged as a major nosocomial pathogen responsible for infections. In this study, we report the molecular characterization, association of insertion sequences and sequence types of clinical isolates of carbapenem ...
Saranya Vijayakumar +15 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
cDNA that encodes active agrin [PDF]
, 1992 Agrin is thought to mediate the motor neuron-induced aggregation of AChRs and AChE on the surface of muscle fibers at neuromuscular junctions. We have isolated a cDNA from a chick brain library that, based on sequence homology and expression experiments,
Bolander +42 more
core +2 more sources
Discovery and genotyping of novel sequence insertions in many sequenced individuals [PDF]
Bioinformatics, 2017 Abstract Motivation Despite recent advances in algorithms design to characterize structural variation using high-throughput short read sequencing (HTS) data, characterization of novel sequence insertions longer than the average read length remains a challenging task.
Kavak, Pinar +6 more
openaire +4 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source