Matching Sequences under Deletion/Insertion Constraints [PDF]
Given two finite sequences, we wish to find the longest common subsequences satisfying certain deletion/insertion constraints. Consider two successive terms in the desired subsequence. The distance between their positions must be the same in the two original sequences for all but a limited number of such pairs of successive terms.
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ISQuest: finding insertion sequences in prokaryotic sequence fragment data [PDF]
Abstract Motivation: Insertion sequences (ISs) are transposable elements present in most bacterial and archaeal genomes that play an important role in genomic evolution. The increasing availability of sequenced prokaryotic genomes offers the opportunity to study ISs comprehensively, but development of efficient and accurate tools is ...
Biswas, Abhishek +3 more
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Background & objectives: Carbapenems are the main antibiotics for the treatment of infections caused by multidrug-resistant (MDR) Pseudomonas aeruginosa (P. aeruginosa).
Maryam Nazari +3 more
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A 19-nucleotide insertion in the leader sequence of avian leukosis virus subgroup J contributes to its replication in vitro but is not related to its pathogenicity in vivo. [PDF]
Subgroup J avian leukosis virus (ALV-J) was first isolated from meat-type chickens that had developed myeloid leukosis and since 2008, ALV-J infections in chickens have become widespread in China.
Xiaolin Ji +7 more
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Role of the N-terminal seven residues of surfactant protein B (SP-B). [PDF]
Breathing is enabled by lung surfactant, a mixture of proteins and lipids that forms a surface-active layer and reduces surface tension at the air-water interface in lungs. Surfactant protein B (SP-B) is an essential component of lung surfactant. In this
Mahzad Sharifahmadian +6 more
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Development of a Biocontained Toluene-Degrading Bacterium for Environmental Protection
Biocontainment is a safeguard strategy for preventing uncontrolled proliferation of genetically engineered microorganisms (GEMs) in the environment. Biocontained GEMs are designed to survive only in the presence of a specific molecule.
Masahito Ishikawa +2 more
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Reconstruction of Sequences Distorted by Two Insertions
Reconstruction codes are generalizations of error-correcting codes that can correct errors by a given number of noisy reads. The study of such codes was initiated by Levenshtein in 2001 and developed recently due to applications in modern storage devices such as racetrack memories and DNA storage.
Zuo Ye +3 more
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Elucidation of the Photorhabdus temperata Genome and Generation of a Transposon Mutant Library To Identify Motility Mutants Altered in Pathogenesis [PDF]
The entomopathogenic nematode Heterorhabditis bacteriophora forms a specific mutualistic association with its bacterial partner Photorhabdus temperata.
Abebe-Akele, Feseha +9 more
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Extended-spectrum cephalosporin-resistant (ESCR) Enterobacteriaceae pose a serious infection control challenge for public health. The emergence of the ESCR phenotype is mostly facilitated by plasmid-mediated horizontal extended-spectrum β-lactamases ...
Apostolos Liakopoulos +10 more
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Site-specific transposition of insertion sequence IS630 [PDF]
IS630 is a 1.15-kilobase sequence in Shigella sonnei that, unlike many mobile elements, seems not to mediate cointegration between different replicons. To assess its transposition, we constructed composite elements containing inverted copies of IS630 flanking a drug resistance gene.
T, Tenzen, S, Matsutani, E, Ohtsubo
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