Results 11 to 20 of about 773,035 (293)
Gram-negative bacteria, especially Enterobacterales, have emerged as major players in antimicrobial resistance worldwide. Resistance may affect all major classes of anti-gram-negative agents, becoming multidrug resistant or even pan-drug resistant ...
Rémy A. Bonnin +20 more
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Inactivation of the lipooligosaccharide (LOS) biosynthesis genes lpxA, lpxC and lpxD by ISAba insertion elements results in high-level resistance to colistin in A. baumannii.
Héctor Olmeda-López +2 more
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Insertion sequences in prokaryotic genomes [PDF]
Insertion sequences (ISs) are small DNA segments that are often capable of moving neighbouring genes. Over 1500 different ISs have been identified to date. They can have large and spectacular effects in shaping and reshuffling the bacterial genome. Recent studies have provided dramatic examples of such IS activity, including massive IS expansion during
Patricia, Siguier +2 more
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Polyclonal spread of blaOXA-23 and blaOXA-58 in Acinetobacter baumannii isolates from Argentina
Background: In order to study the enzymatic carbapenem resistance mechanisms in Acinetobacter baumannii isolates from Argentina, we performed molecular characterization on 41 epidemiologically unrelated strains isolated from 1995 to 2006 with diminished ...
Andrea Karina Merkier +10 more
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IS481EU Shows a New Connection between Eukaryotic and Prokaryotic DNA Transposons
DDD/E transposase gene is the most abundant gene in nature and many DNA transposons in all three domains of life use it for their transposition. A substantial number of eukaryotic DNA transposons show similarity to prokaryotic insertion sequences (ISs ...
Kenji K. Kojima, Weidong Bao
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Insertion Sequence Diversity in Archaea [PDF]
SUMMARYInsertion sequences (ISs) can constitute an important component of prokaryotic (bacterial and archaeal) genomes. Over 1,500 individual ISs are included at present in the ISfinder database (www-is.biotoul.fr), and these represent only a small portion of those in the available prokaryotic genome sequences and those that are being discovered in ...
J, Filée, P, Siguier, M, Chandler
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Polymyxins are one of most important antibiotics available for multidrug-resistant Gram-negative infections. Diverse chromosomal resistance mechanisms have been described, but the polymyxin resistance phenotype is not yet completely understood.
Raquel Girardello +13 more
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Everyman's Guide to Bacterial Insertion Sequences [PDF]
ABSTRACT The number and diversity of known prokaryotic insertion sequences (IS) have increased enormously since their discovery in the late 1960s. At present the sequences of more than 4000 different IS have been deposited in the specialized ISfinder database. Over time it has become increasingly apparent that they are important actors in the
Siguier, Patricia +4 more
openaire +5 more sources
Insertion Sequence IS 900 Revisited [PDF]
ABSTRACT Many studies investigating Mycobacterium avium subsp. paratuberculosis in Crohn's disease have used molecular detection of IS 900 in clinical samples, but some have described polymorphisms in IS 900 as variants of this ...
Makeda, Semret +2 more
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Free-living bacteria have evolved multiple times to become host-restricted endosymbionts. The transition from a free-living to a host-restricted lifestyle comes with a number of different genomic changes, including a massive loss of genes.
Tamara Halter +3 more
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