Scarless excision of an insertion sequence in the OmpK36 promoter restores meropenem susceptibility in a non-carbapenemase-producing Klebsiella pneumoniae [PDF]
Emerging Microbes and InfectionsCarbapenem-resistant Klebsiella pneumoniae (CRKP) poses a significant global health challenge due to its limited treatment options and high mortality rates.
Yingying Du +7 more
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Insertion sequence transposition activates antimycobacteriophage immunity through an lsr2‐silenced lipid metabolism gene island [PDF]
mLifeInsertion sequences (ISs) exist widely in bacterial genomes, but their roles in the evolution of bacterial antiphage defense remain to be clarified. Here, we report that, under the pressure of phage infection, the IS1096 transposition of Mycobacterium ...
Yakun Li +6 more
doaj +2 more sources
Attempts to detect retrotransposition and de novo deletion of Alus and other dispersed repeats at specific loci in the human genome [PDF]
, 2001 Dispersed repeat elements contribute to genome instability by de novo insertion and unequal recombination between repeats. To study the dynamics of these processes, we have developed single DNA molecule approaches to detect de novo insertions at a single
Monckton, D.G. +2 more
core +9 more sources
mSystems, 2019 Extensive drug resistance (XDR) is an escalating global problem. Escherichia coli strain Sanji was isolated from an outbreak of pheasant colibacillosis in Fujian province, China, in 2011.
Xiancheng Zeng +9 more
doaj +3 more sources
Microbiology Spectrum, 2022 Free-living bacteria have evolved multiple times to become host-restricted endosymbionts. The transition from a free-living to a host-restricted lifestyle comes with a number of different genomic changes, including a massive loss of genes.
Tamara Halter +3 more
doaj +1 more source
Molecular Plant-Microbe Interactions, 2004 Bacterial wilt, caused by Ralstonia solanacearum, is a serious disease of tobacco in North and South Carolina. In contrast, the disease rarely occurs on tobacco in Georgia and Florida, although bacterial wilt is a common problem on tomato.
Alison E. Robertson +4 more
doaj +1 more source
ISPst9, an ISL3-like insertion sequence from Pseudomonas stutzeri AN10 involved in catabolic gene inactivation [PDF]
, 2008 A novel insertion sequence (IS), ISPst9, from Pseudomonas stutzeri AN10 was cloned and characterized. ISPst9 is a typical bacterial IS, consisting of a 2472-bp element flanked by 24-bp perfect inverted repeats that generates 8-bp AT-rich target ...
Martín-Cardona, Cèlia +7 more
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Glycosylation can influence topogenesis of membrane proteins and reveals dynamic reorientation of nascent polypeptides within the translocon [PDF]
, 1999 The topology of multispanning membrane proteins in the mammalian endoplasmic reticulum is thought to be dictated primarily by the first hydrophobic sequence.
Martin Spiess +5 more
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GABI-Kat SimpleSearch: new features of the Arabidopsis thaliana T-DNA mutant database [PDF]
, 2011 Kleinbölting N, Huep G, Klotgen A, Viehöver P, Weisshaar B. GABI-Kat SimpleSearch: new features of the Arabidopsis thaliana T-DNA mutant database. Nucleic Acids Research.
Viehöver, Prisca +9 more
core +1 more source
On dynamic delay and repeater insertion in distributed capacitively coupled interconnects. [PDF]
, 2002 Repeater insertion is a well established technique to minimise the propagation delay over long resistive interconnects. In deep sub-micron technologies, as the wires are spaced ever closer and signal rise and fall times go into the sub-nanosecond region,
Tenhunen, Hannu, Pamunuwa, Dinesh B.
core +4 more sources