Results 21 to 30 of about 2,230,593 (247)

Dynamic insertion of membrane proteins at the endoplasmic reticulum [PDF]

open access: yes, 2005
Most eukaryotic membrane proteins are cotranslationally integrated into the endoplasmic reticulum membrane by the Sec61 translocation complex. They are targeted to the translocon by hydrophobic signal sequences which induce the translocation of either ...
Higy, Marie
core   +1 more source

Screening of Arabidopsis mutants for functional genomic studies [PDF]

open access: yes, 2008
Eight photosynthetic Arabidopsis mutants were screened for co-segregation of a photosynthetic phenotype with the T-DNA insertion. These mutants were selected from 80 photosynthetic mutants with genetic background of Columbia-0.
Leister, Dario   +6 more
core   +1 more source

Neutron diffraction reveals sequence-specific membrane insertion of pre-fibrillar islet amyloid polypeptide and inhibition by rifampicin [PDF]

open access: yes, 2005
Human islet amyloid polypeptide (hIAPP) forms amyloid deposits in non-insulin-dependent diabetes mellitus (NIDDM). Pre-fibrillar hIAPP oligomers (in contrast to monomeric IAPP or mature fibrils) increase membrane permeability, suggesting an important ...
Bradshaw, Jeremy P.   +14 more
core   +1 more source

Detecting rare structural variation in evolving microbial populations from new sequence junctions using breseq

open access: yesFrontiers in Genetics, 2015
New mutations leading to structural variation (SV) in genomes — in the form of mobile element insertions, large deletions, gene duplications, and other chromosomal rearrangements — can play a key role in microbial evolution.
Daniel E Deatherage   +3 more
doaj   +1 more source

Genome- and transcriptome-assisted development of nuclear insertion/deletion markers for Calanus species (Copepoda: Calanoida) identification [PDF]

open access: yes, 2014
Copepods of the genus Calanus are key zooplankton species in temperate to arctic marine ecosystems. Despite their ecological importance, species identification remains challenging.
Poortvliet, Marloes   +29 more
core   +1 more source

Draft Genome Sequence of an Escherichia coli O157:H43 Strain Isolated from Cattle [PDF]

open access: yes, 2013
Here we report the draft genome sequence of an Escherichia coli O157:H43 strain, designated T22, with an atypical virulence gene profile and isolated from healthy cattle.
Maróti, Gergely   +4 more
core   +1 more source

Functional constraint and small insertions and deletions in the ENCODE regions of the human genome. [PDF]

open access: yes, 2007
BACKGROUND: We describe the distribution of indels in the 44 Encyclopedia of DNA Elements (ENCODE) regions (about 1% of the human genome) and evaluate the potential contributions of small insertion and deletion polymorphisms (indels) to human genetic ...
Cooper, GM   +17 more
core   +1 more source

The Role of Insertion Sequence (IS) Elements in Inactivation of Outer Membrane Porin OprD and Resistance to Carbapenems among Pseudomonas aeruginosa Clinical Strains in Ardabil

open access: yesJournal of Ardabil University of Medical Sciences, 2021
Background & objectives: Carbapenems are the main antibiotics for the treatment of infections caused by multidrug-resistant (MDR) Pseudomonas aeruginosa (P. aeruginosa).
Maryam Nazari   +3 more
doaj  

Multiple determinants direct the orientation of signal-anchor proteins : the topogenic role of the hydrophobic signal domain [PDF]

open access: yes, 1997
The orientation of signal-anchor proteins in the endoplasmic reticulum membrane is largely determined by the charged residues flanking the apolar, membrane-spanning domain and is influenced by the folding properties of the NH2-terminal sequence. However,
Martin Spiess   +3 more
core   +1 more source

Early steps in mitochondrial protein import [PDF]

open access: yes, 1990
The process of insertion of precursor proteins into mitochondrial membranes was investigated using a hybrid protein (pSc1-c) that contains dual targeting information and, at the same time, membrane insertion activity.
Stuart, Rosemary A.   +2 more
core   +1 more source

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