Results 101 to 110 of about 4,038 (203)

Distinct activation modes of the Relaxin Family Peptide Receptor 2 in response to insulin-like peptide 3 and relaxin

Scientific Reports, 2017
Relaxin family peptide receptor 2 (RXFP2) is a GPCR known for its role in reproductive function. It is structurally related to the human relaxin receptor RXFP1 and can be activated by human gene-2 (H2) relaxin as well as its cognate ligand insulin-like ...
Shoni Bruell, Ashish Sethi, Nicholas Smith, Daniel J. Scott, Mohammed Akhter Hossain, Qing-Ping Wu, Zhan-Yun Guo, Emma J. Petrie, Paul R. Gooley, Ross A. D. Bathgate   +9 more
doaj   +1 more source

RETRACTION: Effects of Osteocalcin on Synthesis of Testosterone and INSL3 during Adult Leydig Cell Differentiation

International Journal of Endocrinology, Volume 2026, Issue 1, 2026.
International Journal of Endocrinology
wiley   +1 more source

Dysregulation of granulosal bone morphogenetic protein receptor 1B density is associated with reduced ovarian reserve and the age-related decline in human fertility [PDF]

, 2016
Reproductive ageing is linked to the depletion of ovarian primordial follicles, which causes an irreversible change to ovarian cellular function and the capacity to reproduce.
Almahbobi, Ghanim, Arfuso, Frank, Dharmarajan, Arun, Knight, Phil G., Leung, Yee, Regan, Sheena L. P., Stanger, James D., Yovich, John L.   +7 more
core   +1 more source

Effects of Osteocalcin on Synthesis of Testosterone and INSL3 during Adult Leydig Cell Differentiation

International Journal of Endocrinology, 2019
Proliferation and differentiation of adult Leydig cells are mainly completed in puberty. In many studies, apart from normal postnatal development process, it is widely indicated that, through administrating EDS, Leydig cell population is eliminated and ...
Gulfidan Coskun, Leman Sencar, Abdullah Tuli, Dilek Saker, Mustafa Muhlis Alparslan, Sait Polat   +5 more
doaj   +1 more source

Searching for candidate genes for male infertility [PDF]

, 2003
Aim: We describe an approach to search for candidate genes for male infertility using the two human genome databases: the public University of California at Santa Cruz (UCSC) and private Celera databases which list known and predicted gene sequences and ...
Armes, JE, Baker, HWG, Moses, EK, Truong, BN, Venter, DJ   +4 more
core  

Association between maternal exposure to di(2-ethylhexyl) phthalate and reproductive hormone levels in fetal blood: the Hokkaido study on environment and children's health.

PLoS ONE, 2014
Prenatal di(2-ethylhexyl) phthalate (DEHP) exposure can produce reproductive toxicity in animal models. Only limited data exist from human studies on maternal DEHP exposure and its effects on infants.
Atsuko Araki, Takahiko Mitsui, Chihiro Miyashita, Tamie Nakajima, Hisao Naito, Sachiko Ito, Seiko Sasaki, Kazutoshi Cho, Tamiko Ikeno, Katsuya Nonomura, Reiko Kishi   +10 more
doaj   +1 more source

Importância do estudo multigénico no diagnóstico molecular de doenças raras por sequenciação de nova geração [PDF]

, 2019
Introdução: A sequenciação de nova geração (NGS) revolucionou o diagnóstico molecular das doenças raras (DR) proporcionando a análise de um maior número de genes, resultados mais rápidos e custos reduzidos. A NGS usando diferentes abordagens, possibilita
Gonçalves, João, Oliveira, Beatriz, Pereira Caetano, Iris, Rodrigues, Pedro, Theisen, Patrícia   +4 more
core  

Possible association of serum trimethylamine N-oxide and INSL3 levels with the gut–testis axis in cryptorchidism

Discover Medicine
Cryptorchidism, a common congenital condition in male children, has been associated with impaired testicular function and increased risk of infertility.
Derya Ayvaci, Fadime Ovali, Mehmet Sarikaya, Metin Gunduz, Husamettin Vatansev   +4 more
doaj   +1 more source

Association between COVID-19 status and Leydig cell functional capacity among men in hospitalized cohorts

The Aging Male
Background The first wave of the COVID-19 pandemic in the UK in 2020 led to significant morbidity, hospitalization, and death, particularly amongst elderly men.
Ravinder Anand-Ivell, Xinyuan Yang, Alexander W. Tarr, William I. Irving, David J. Clark, Henry M. Staines, Yolanda Augustin, Sanjeev Krishna, Richard Ivell   +8 more
doaj   +1 more source

Prepubertal nutrition alters Leydig cell functional capacity and timing of puberty.

PLoS ONE, 2019
Leydig cell functional capacity reflects the numbers and differentiation status of the steroidogenic Leydig cells in the testes and becomes more or less fixed in early adulthood with the final establishment of the hypothalamo-pituitary-gonadal (HPG) axis
Ravinder Anand-Ivell, Colin J Byrne, Jonas Arnecke, Sean Fair, Pat Lonergan, David A Kenny, Richard Ivell   +6 more
doaj   +1 more source