Results 181 to 190 of about 4,038 (203)

Testicular descent: INSL3, testosterone, genes and the intrauterine milieu

Nature Reviews Urology, 2011
Complete testicular descent is a sign of, and a prerequisite for, normal testicular function in adult life. The process of testis descent is dependent on gubernacular growth and reorganization, which is regulated by the Leydig cell hormones insulin-like peptide 3 (INSL3) and testosterone.
Bay, Katrine, Main, Katharina M, Toppari, Jorma, Skakkebæk, Niels E   +3 more
openaire   +5 more sources

INSL3 in the benign hyperplastic and neoplastic human prostate gland

International Journal of Oncology, 2005
The human prostate gland is a well known source of H1 and H2 relaxin but information is lacking on the expression and potential role of the INSL3 peptide hormone within the prostate gland. In the present study we have investigated the expression of human INSL3 in patients with benign prostate hyperplasia (BPH), prostate intraepithelial neoplasia (PIN ...
Thomas, Klonisch, Harald, Müller-Huesmann, Maria, Riedel, Astrid, Kehlen, Joanna, Bialek, Yvonne, Radestock, Hans-Juergen, Holzhausen, Klaus, Steger, Martin, Ludwig, Wolfgang, Weidner, Cuong, Hoang-Vu, Sabine, Hombach-Klonisch   +11 more
openaire   +2 more sources

Loss of Insl3 : A Potential Predisposing Factor for Testicular Torsion

Journal of Urology, 2010
The testicular hormone Insl3 is critical for mouse gubernacular development. Knockout mice exhibit bilateral intra-abdominal cryptorchidism with absent gubernaculum. Prior studies described torsion of the vas deferens in Insl3 mutant mice. We performed a detailed anatomical analysis of the vas deferens and testis in Insl3 mutant mice to characterize ...
Sozubir, Selami, Barber, Theodore, Wang, Yi, Ahn, Chul, Zhang, Shaohua, Verma, Sunita, Lonergan, Devin, Lorenzo, Armando J., Nef, Serge, Baker, Linda A.   +9 more
openaire   +3 more sources

INSL3 Expression in Leydig Cell Hyperplasia and Leydig Cell Tumors

Applied Immunohistochemistry & Molecular Morphology, 2019
Insulin-like 3 (INSL3) is a hormone produced by Leydig cells (LCs) and leads to physiological testicular descent during embryonic development. We investigated the expression of INSL3 by immunohistochemistry in normal LCs, in Leydig cell tumor (LCT) (n=17 including 15 testes and 2 ovaries) and in Leydig cell hyperplasia (LCH) (n=10).
Nelli S, Lakis, Kara A, Lombardo, Shamlal, Mangray, George J, Netto, Daniela, Salles, Andres, Matoso   +5 more
openaire   +2 more sources

INSL3

2021
openaire   +1 more source

Dynamics of INSL3 peptide expression in the rodent testis.

Biology of reproduction, 2010
The Leydig cell-specific factor insulin-like peptide 3 (INSL3) is involved in testicular descent during embryo development, and has been suggested to regulate spermatogenesis and bone metabolism in the adult. Using a new, sensitive assay specific for rodent INSL3, we have mapped the secretion of INSL3 into peripheral blood in mice and during postnatal ...
Anand Ivell, R., Heng, K., Hafen, B., Setchell, B., Ivell, R.   +4 more
openaire   +2 more sources

Insulin-like peptide 3 (INSL3)

2019
Ravinder Anand-Ivell, Richard Ivell
openaire   +1 more source

Evidence for existence of insulin-like factor 3 (INSL3) hormone-receptor system in the ovarian corpus luteum and extra-ovarian reproductive organs during pregnancy in goats

Cell and Tissue Research, 2021
Keiichiro Kizaki, Tetsuya Kohsaka
exaly  

Insulin-like peptide 3 (INSL3) is a major regulator of female reproductive physiology

Human Reproduction Update, 2018
Richard Ivell, Ravinder Jk Anand-Ivell
exaly  

Increase in final stages of follicular atresia and premature decay of corpora lutea in Insl3-deficient mice

Molecular Reproduction and Development, 2001
Ibrahim M Adham
exaly