Results 31 to 40 of about 603,213 (294)
Distributed Learning System Design: A New Approach and an Agenda for Future Research [PDF]
, 2006 This article presents a theoretical framework designed to guide distributed learning design, with the goal of enhancing the effectiveness of distributed learning systems.
Bell, Bradford S. +1 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
“Instructional design” as a system-forming category: approaches and definitions
Вестник Мининского университета, 2023 Introduction. The article is devoted to the essence of the concept of "instructional design". In the course of the study, scientific sources, experience and speeches of educational content developers were analyzed in order to clarify the interpretation ...
M. E. Vayndorf-Sysoeva +1 more
doaj +1 more source
Oral reading: practices and purposes in secondary classrooms [PDF]
, 2018 PURPOSE This paper aims to investigate teacher-initiated whole-group oral reading practices in two ninth-grade reading intervention classrooms and how teachers understood the purposes of those practices.
Brooks, Maneka Deanna +1 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Developing Mathematics-Students Worksheet Based On Realistic Approach For Junior High School In Bilingual Program [PDF]
, 2011 The aim of this study is to develop mathematics-student worksheet based on realistic approach for junior high school in bilingual program. The criteria used to generate product are valid and practical.
Ariyadi, Wijaya +2 more
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Instructional Design for Students with Visual Impairments in English Learning [PDF]
, 2011 Mastering English has become one important skill for students in higher education, especially in university level. As the impact, every university provides English program for students in the faculty or language center.
Aryanti, W. (Widya), Farani, R. (Rizki)
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Exploring Standards of Rigour for Design Cases [PDF]
, 2009 Designers share their specialized knowledge by developing design cases, which we define as representations of design efforts and outcomes disseminated to peers. In the field of instructional design this practice is not well established. In addition, many
Boling, Elizabeth, Smith, Kennon M
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