Results 41 to 50 of about 53,517 (248)

Maximizing the impact of dialogic peer feedback on student engagement: The role of regulation support

open access: yesEducational Technology & Society
The absence of instructional support during peer feedback prevents students from engaging with peer feedback. This study adopted regulated dialogic feedback as the instructional foundation and investigated its impact on students’ engagement using an ...
Sheng-Shiang Tseng, Erkan Er
doaj   +1 more source

Exploring teachers’ instructional practices for literacy in English in Grade 1: A case study of two urban primary schools in the Shiselweni region of Eswatini (Swaziland)

open access: yesReading & Writing, 2019
Background: Literacy education in the foundation phase is a global concern. Studies have shown that mastering literacy in the first three years of school ensured academic success and lack of it had negative effects academically, socially and economically.
Patience Dlamini, Ayub Sheik
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Disaster Risk Reduction through school learners’ awareness and preparedness

open access: yesJàmbá, 2012
In 2006, the ISDR (International Strategy for Disaster Reduction) (2007) initiated a campaign called Disaster Risk Reduction Begins at School to encourage the integration of disaster risk education into school curricula in countries vulnerable to ...
Takalani S. Rambau   +2 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Incorporating teacher effect when modeling student engagement in smart STEM classrooms: a cluster analysis

open access: yesSmart Learning Environments
Student engagement during learning serves as a critical predictor of academic success and plays a pivotal role in nurturing interest and readiness for future careers. As digital platforms become increasingly important to learning, it is essential that we
Kelly Shreeve   +8 more
doaj   +1 more source

A systematic review of AI education in K-12 classrooms from 2018 to 2023: Topics, strategies, and learning outcomes

open access: yesComputers and Education: Artificial Intelligence
AI education aims to teach AI concepts, essential knowledge, and skills related to the fundamental ideas in AI. As AI becomes increasingly prevalent in our daily lives, schools and educators have started to recognize the importance of AI education in K ...
Sang Joon Lee, Kyungbin Kwon
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Investigation of users’ opinions, perceptions and attitudes towards the use of artificial intelligence in online learning environments

open access: yesEURODL
The impact and importance of AI are being increasingly recognised, although there are still uncertainties regarding its innovative potential. These same uncertainties and effects are also evident in educational contexts.
Hamza Aydemir, Süleyman Sadi Seferoğlu
doaj   +1 more source

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