Results 61 to 70 of about 10,982,042 (291)

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

Maximizing the impact of dialogic peer feedback on student engagement: The role of regulation support

open access: yesEducational Technology & Society
The absence of instructional support during peer feedback prevents students from engaging with peer feedback. This study adopted regulated dialogic feedback as the instructional foundation and investigated its impact on students’ engagement using an ...
Sheng-Shiang Tseng, Erkan Er
doaj   +1 more source

Exploring teachers’ instructional practices for literacy in English in Grade 1: A case study of two urban primary schools in the Shiselweni region of Eswatini (Swaziland)

open access: yesReading & Writing, 2019
Background: Literacy education in the foundation phase is a global concern. Studies have shown that mastering literacy in the first three years of school ensured academic success and lack of it had negative effects academically, socially and economically.
Patience Dlamini, Ayub Sheik
doaj   +1 more source

Authentic E-Learning in higher education: Design principles for authentic learning environments and tasks [PDF]

open access: yes, 2006
With many learners failing to engage with didactic and outmoded instructional methods, and unwilling to use technology that simply replicates the one-way transfer of information from teacher to student, authentic learning designs have the potential to ...
Herrington, J.
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

A systematic review of AI education in K-12 classrooms from 2018 to 2023: Topics, strategies, and learning outcomes

open access: yesComputers and Education: Artificial Intelligence
AI education aims to teach AI concepts, essential knowledge, and skills related to the fundamental ideas in AI. As AI becomes increasingly prevalent in our daily lives, schools and educators have started to recognize the importance of AI education in K ...
Sang Joon Lee, Kyungbin Kwon
doaj   +1 more source

Disaster Risk Reduction through school learners’ awareness and preparedness

open access: yesJàmbá, 2012
In 2006, the ISDR (International Strategy for Disaster Reduction) (2007) initiated a campaign called Disaster Risk Reduction Begins at School to encourage the integration of disaster risk education into school curricula in countries vulnerable to ...
Takalani S. Rambau   +2 more
doaj   +1 more source

Instructional technology research, design and development: lessons from the field

open access: yes, 2012
This book is about design and development in Instructional Technology Design and development research (Richey & Klein, 2007), or was formerly known as developmental research (Richey, Klein & Nelson, 2004) is an emerging form of research in the field of

core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Η αναγκαιότητα της καθοδηγητικής στρατηγικής στις βιβλιοθήκες των εκπαιδευτικών ιδρυμάτων [PDF]

open access: yes, 2005
In the season of electronic information it is required the re-examination of library scientists' role. The libraries supposed to be involved in the educational process, that is to participate in the process of growth of instructional strategy, as ...
Κορομπίλη, Στέλλα
core   +1 more source

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