Tissue Transglutaminase Facilitates the Polymerization of Insulin-like Growth Factor-binding Protein-1 (IGFBP-1) and Leads to Loss of IGFBP-1's Ability to Inhibit Insulin-like Growth Factor-I-stimulated Protein Synthesis [PDF]
, 2001 Keiji Sakai +3 more
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Insulin-Like Growth Factor-1 and Central Neurodegenerative Diseases
Endocrinology and Metabolism Clinics of North America, 2012 The previously undisputed neuroprotective role of insulin-like growth factor 1 (IGF-1) has been challenged by recent observations in IGF-1 receptor (IGF-1R) defective mutants. As new ligand-dependent and ligand-independent roles for IGF-1R are now emerging, new insights into the biologic role of brain IGF-1R and its connection with serum and brain IGF ...
openaire +3 more sources
Tonsillectomy and Weight Gain in Children, Is There a Correlation? [PDF]
, 2013 The relationship between tonsillectomy and postoperative weight gain in children has been studied across the globe. Indications for tonsillectomy include chronic recurrent tonsillitis and obstructive sleep apnea.
Doucette, Jacqueline M
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Advanced Healthcare Materials, EarlyView.Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen +9 more
wiley +1 more source
Insulin-Like Growth Factor 1 Physiology [PDF]
Endocrinology and Metabolism Clinics of North America, 2012 Shoshana Yakar, Martin L. Adamo
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Insulin-Like growth-factor 1 myocardial expression decreases in chronic alcohol consumption
, 2013 Background Chronic alcohol ingestion may cause severe biochemical and pathophysiological derangements to skeletal muscle. Unfortunately, these alcohol-induced events may also prime skeletal muscle for worsened, delayed, or possibly incomplete repair ...
Antúnez Jorge, Emilia +3 more
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Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Advanced Healthcare Materials, EarlyView.Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
Activation of human insulin-like growth factor binding protein-1 gene promoter by a distal regulatory sequence in a human endometrial adenocarcinoma cell line. [PDF]
, 1995 Jingxia Gao, James Mazella, Linda Tseng
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890 Does insulin-like growth factor (IGF-1) gene polymorphism affect acne? [PDF]
, 2023 Unaiza Iftikhar
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Fibrillar Bundles as Fibrous Filler Materials for Attaining Cell Anisotropy in Bioprinting
Advanced Healthcare Materials, EarlyView.Fibrillar bundles are introduced as a bioprintable additive that enables robust and scalable cellular alignment within 3D constructs through flow‐induced orientation during extrusion. These fibers support strong cell adhesion and polarization across various cell types and significantly enhance myotube alignment in Gelatine‐Methacryloyl (GelMA ...
Sven Heilig +10 more
wiley +1 more source