Results 11 to 20 of about 14,817,072 (278)

Pan‐cancer analysis of oncogenic role of insulin‐like growth factor‐binding proteins and validation in ovarian cancer [PDF]

Cancer Medicine, 2023
Background Numerous studies have shown that the insulin‐like growth factor (IGF) pathway is highly associated with tumor initial and progression in several tumors.
Wei Tan, Jie Zhang, Zhimin Deng, Fangfang Dai, Lujia Tang, Wei Hu, Hua Liu   +6 more
doaj   +2 more sources

Association between serum levels of insulin-like growth factor-binding proteins at admission and outcomes at 3 months after acute ischemic stroke [PDF]

Annals of Medicine
Background Insulin-like growth factor-binding proteins (IGFBPs) contribute to central nervous system development and may influence recovery after stroke.
Yuyi Zhu, Huan Wang, Ting Cui, Mingxi Chen, Yaqi Chen, Simiao Wu, Zilong Hao, Shihong Zhang, Xinyi Leng, Deren Wang   +9 more
doaj   +2 more sources

Effectiveness of low-fat diet on the levels of insulin-like growth factor-1 and insulin-like growth factor binding proteins: a systematic review and meta-analysis of randomized controlled clinical trials [PDF]

Journal of Health, Population and Nutrition
Background Previous researches on the effect of low-fat diet (LF) on insulin-like growth factor-1 (IGF-1), and its binding proteins (IGFBPs) did not reach a consensus result, and there is no study summarizing these findings.
Zohreh Sadat Sangsefidi, Sepideh Soltani, Fatemeh Meshkini, Kimia Torabynasab, Sheida Zeraattalab-Motlagh, Elham Razmpoosh, Mahdi Hejazi, Masoumeh Khalighi Sikaroudi, Shima Abdollahi   +8 more
doaj   +2 more sources

Fasting Induces Gene Expression of Insulin-like Growth Factor-binding Proteins in Skeletal Muscles of Chicks [PDF]

The Journal of Poultry Science
In mammals, evidence suggests that insulin-like growth factor-binding proteins (IGFBPs) affect skeletal muscle growth in an autocrine and paracrine manner.
Asmaa S. El-far, Haruki Osada, Yumi Sakanashi, Takaoki Saneyasu, Kazuhisa Honda   +4 more
doaj   +2 more sources

Cellular Actions of the Insulin-Like Growth Factor Binding Proteins [PDF]

Endocrine Reviews, 2002
In addition to their roles in IGF transport, the six IGF-binding proteins (IGFBPs) regulate cell activity in various ways. By sequestering IGFs away from the type I IGF receptor, they may inhibit mitogenesis, differentiation, survival, and other IGF-stimulated events.
Robert Baxter, Sue M Firth
exaly   +3 more sources

Insulin-Like Growth Factor Binding Proteins and IGFBP Proteases: A Dynamic System Regulating the Ovarian Folliculogenesis [PDF]

Frontiers in Endocrinology, 2018
The aim of the present article is to update our understanding of the expression of the insulin-like growth factor binding proteins (IGFBPs), IGFBP proteases and their implication in the different processes of ovarian folliculogenesis in mammals.
Sabine Mazerbourg, Philippe Monget
doaj   +2 more sources

Regulation of human fibroblast insulin-like growth factor (IGF)-binding proteins by IGF-1 and cytokines, mechanisms of action and effects upon IGF bioactivity [PDF]

, 1995
PhDThe insulin-like growth factors, IGF-I and IGF-II, are ubiquitous polypeptide molecules that have mitogenic and metabolic actions in a wide variety of cell types, and consequently play a major role in mammalian growth and development.
Yateman, Martin Edward
core   +4 more sources

Associations of insulin and insulin-like growth factors with physical performance in old age in the boyd orr and caerphilly studies. [PDF]

, 2012
OBJECTIVE: Insulin and the insulin-like growth factor (IGF) system regulate growth and are involved in determining muscle mass, strength and body composition.
David Gunnell, Gunnell, David, Gallacher, John, Martin, Richard M., Birnie, K, Gunnell, D, Kate Birnie, Gunnell David, Antony Bayer, Bayer Antony, John Gallacher, Ebrahim, S, Holly, Jeff MP, Bayer, A, Yoav Ben-Shlomo, Birnie Kate, Shah Ebrahim, Ben-Shlomo, Y, Ebrahim, Shah, Jeff M P Holly, Gunnell, DJ, Gallacher, J, Martin, Richard M, Holly, JM, Bayer, Antony, Jeff M. P. Holly, Martin Richard M., Martin, RM, Richard M Martin, Richard M. Martin, Holly Jeff M. P., Gallacher John, Holly, JMP, Holly, Jeff M. P., Bayer, Antony James, Birnie, Kate, Ben-Shlomo, Yoav, Ben-Shlomo Yoav, Ebrahim Shah, Gallacher, John Edward   +39 more
core   +5 more sources

Cumulative mutagenesis of the basic residues in the 201-218 region of insulin-like growth factor (IGF)-binding protein-5 results in progressive loss of both IGF-I binding and inhibition of IGF-I biological action [PDF]

, 2005
We have reported previously that mutation of two conserved nonbasic amino acids (G203 and Q209) within the highly basic 201–218 region in the C-terminal domain of IGF-binding protein-5 (IGFBP-5) decreases binding to IGFs.
Kelly, S.M., Tonner, Elizabeth, Gow, I.F., Gow, Iain F, Clegg, Roger A, Allan, Gordon J., Clegg, Roger A., Beattie, J., Beattie, James, Flint, David J., Allan, G.J., Flint, D.J., Gow, Iain F., Shand, J., Tonner, E., Szymanowska, M., Phillips, K., Shand, John H, Allan, Gordon J, Phillips, Kirsten, Kelly, Sharon M, Clegg, R.A., Shand, John H., Flint, David J, Szymanowska, Malgorzata, Kelly, Sharon M.   +25 more
core   +4 more sources

Thermal stress impaired expression of insulin-like growth factor binding proteins in pigs

Indian Journal of Animal Sciences, 2023
This study aimed to investigate the correlation of IGFs, IGFBPs, and IGFBPRs of grower pigs with change in temperature humidity index (THI). THI was calculated to know the months of the year when pigs feel discomfort and samples of feed offered were ...
S BORAH, S SOREN, R TALUKDAR, L KALITA, K PAME, A J NATH, B BORAH, P K PATHAK, B N BHATTACHARRYYA   +8 more
doaj   +1 more source