Results 21 to 30 of about 200,349 (246)
Insulin-like growth factor (IGF)-I and IGF binding proteins axis in diabetes mellitus [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2015 Increasing evidence suggests an important role of the insulin-like growth factor (IGF)-IGF binding protein (IGFBP) axis in the maintenance of normal glucose and lipid metabolism. Significant changes occur in the local IGF-I-IGFBPs environment in response
Min Sun Kim, Dae-Yeol Lee
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Cellular Actions of Insulin-Like Growth Factor Binding Proteins [PDF]
Hormone and Metabolic Research, 1999 The insulin-like growth factors (IGFs), insulin-like growth factor binding proteins (IGFBPs), and the IGFBP proteases are involved in the regulation of somatic growth and cellular proliferation both in vivo and in vitro. IGFs are potent mitogenic agents whose actions are determined by the availability of free IGFs to interact with the IGF receptors ...
R J, Ferry +4 more
openaire +2 more sources
Advanced Biomedical Research, 2015 Background: The effect of the growth hormone on target cells is mediated by the insulin-like growth factor 1 (IGF-1). IGF-1 binds to the insulin-like growth factor binding proteins (IGFBPs) in blood and biological fluids.
Emad Khodadadi +4 more
doaj +1 more source
The Role of Insulin-Like Growth Factors and Insulin-Like Growth Factor-Binding Proteins in the Nervous System. [PDF]
Biochem Insights, 2019 The insulin-like growth factors (IGF-I and IGF-II) and their receptors are widely expressed in nervous tissue from early embryonic life. They also cross the blood brain barriers by active transport, and their regulation as endocrine factors therefore differs from other tissues.
Lewitt MS, Boyd GW.
europepmc +4 more sources
IGFBP-1 marker of cervical ripening and predictor of preterm birth [PDF]
Medicinski Glasnik, 2016 Aim To establish a correlation between positive values of IGFBP-1 (>10 mg/L, Actim Partus Test, APT) and premature cervical ripening in imminent preterm labor. Methods A prospective study was conducted in primary health care centers in Tuzla, Gynecology
Larisa Mešić Ðogić +4 more
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Przegląd Dermatologiczny, 2020 Insulin-like growth factor 1 belongs to the group of polypeptide growth factors. It plays a special role in the regulation of pre- and postnatal growth of the organism, and also has a hypoglycaemic, neuro-, and osteo- and chondroprotective effect ...
Magda Marek-Safiejko +3 more
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Reproductive Biology and Endocrinology, 2022 Insulin-like growth factor 2 (IGF2) mRNA binding proteins (IMPs) family belongs to a highly conserved family of RNA-binding proteins (RBPs) and is responsible for regulating RNA processing including localization, translation and stability. Mammalian IMPs
Xiao Xu +3 more
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Insulin-like growth factor-I and its binding proteins in healthy mothers and their newborns [PDF]
Einstein (São Paulo), 2004 Objective: To determine serum levels of insulin-like growth factor-I, free insulin-like growth factor-I and its binding proteins in maternalserum and in cord blood of two groups of newborns with differentbirth weights.
Rosanna Velleca Lima +3 more
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Breast Cancer Research, 2019 Background Mammographic density (MD) is a strong breast cancer risk factor that reflects fibroglandular and adipose tissue composition, but its biologic underpinnings are poorly understood. Insulin-like growth factor binding proteins (IGFBPs) are markers
Manila Hada +18 more
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Insulin-like growth factor binding proteins increase intracellular calcium levels in two different cell lines. [PDF]
PLoS ONE, 2013 BACKGROUND: Insulin-like growth factor binding proteins (IGFBPs) are six related secreted proteins that share IGF-dependent and -independent functions.
Danielle Seurin +4 more
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