Results 251 to 260 of about 34,204,101 (306)
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Insulin‐like growth factor I actions on steroidogenesis
Acta Paediatrica, 1994The best evidence that insulin‐like growth factor I (IGF‐I) contributes to normal steroidogenesis comes from patients with growth hormone (GH) insensitivity syndrome due to deletion of the GH receptor gene. These patients have severe GH resistance and severe IGF‐I insufficiency, and present with markedly delayed puberty without gonadotrophin ...
Chatelain, P.G. +7 more
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Colocalization of insulin-like growth factor-binding protein with insulin-like growth factor I
American Journal of Physiology-Renal Physiology, 1991We report the localization of insulin-like growth factor I (IGF-I) and a 25-kDa form of insulin-like growth factor-binding protein (IGF-BP-1) in adult rat kidney. The antigens were localized using a rabbit anti-human IGF-I antibody, and a rabbit anti-human IGF-BP-1 antibody raised against human 25-kDa IGF-BP-1 purified from amniotic fluid ...
S, Kobayashi +2 more
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Insulin‐like growth factor I in growing thoroughbreds
Journal of Animal Physiology and Animal Nutrition, 2007SummaryThe objective of this longitudinal study was to characterize growth and plasma insulin‐like growth factor I (IGF‐I) concentrations in pasture‐raised thoroughbreds fed two sources of dietary energy. Mares and foals were randomly assigned to either a sugar and starch (SS) or fat and fibre (FF)‐rich feed, and plasma IGF‐I and growth were measured ...
W B, Staniar +3 more
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Insulin-Like Growth Factor-I in Celiac Disease
Journal of Pediatric Gastroenterology and Nutrition, 1994To contribute to the description of the physiopathological mechanisms of celiac disease, changes in insulin-like growth factor I (IGF-I) were followed-up in 21 children suspected of suffering from celiac disease. Thirteen children were suffering from celiac disease according to the original criteria of the European Society of Paediatric ...
B, Weile +3 more
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Insulin-Like Growth Factor I: Pros and Cons of a Bioassay
Hormone Research in Paediatrics, 2011Background: Insulin-like growth factor I (IGF-I) immunoassays are primarily used to estimate IGF-I status. Recently an IGF-I-specific kinase receptor activation assay (KIRA) was developed as an alternative method for measuring IGF-I bioactivity. When compared with IGF-I immunoassays, the IGF-I KIRA has the theoretical advantage of measuring the net ...
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Exercise and Circulating Insulin-Like Growth Factor I
Hormone Research in Paediatrics, 2004Determinations of serum concentrations of total insulin-like growth factor I (tIGF-I) are important in the diagnosis, monitoring of treatment and safety evaluation of patients with growth disorders and/or metabolic disease. It is well established that tIGF-I status varies over time.
Ulrika, Berg, Peter, Bang
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Peptides, 1993
Recombinant human insulin-like growth factor I (hIGF-I) was reacted with azidobenzoyl hydroxysuccinimide to produce a mixture of photoactive hIGF-I derivatives. The mixture was purified by reversed-phase HPLC to yield three mono-substituted azidobenzoyl hIGF-Is.
Cecil C. Yip +3 more
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Recombinant human insulin-like growth factor I (hIGF-I) was reacted with azidobenzoyl hydroxysuccinimide to produce a mixture of photoactive hIGF-I derivatives. The mixture was purified by reversed-phase HPLC to yield three mono-substituted azidobenzoyl hIGF-Is.
Cecil C. Yip +3 more
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Insulin-like growth factor-I and diabetes. A review
Growth Hormone & IGF Research, 1998Although diabetes is a heterogeneous condition, IGF-I has been shown to improve glycaemic control and reduce insulin requirements in both IDDM and NIDDM. In IDDM, the therapeutic rationale for IGF-I is as a replacement therapy "topping up" low circulating IGF-I levels.
Simpson, H L +2 more
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Effects of Insulin‐Like Growth Factor I in Man
Acta Paediatrica, 1990ABSTRACT. A 6‐day period of subcutaneous infusion with recombinant human insulin‐like growth factor I in three healthy male volunteers resulted in an increase in the ratio of insulin to C‐peptide levels and significant decreases in triglyceride levels and the ratio of total to high density lipoprotein—cholesterol in serum.
Guler HP, Schmid C, Zapf J, Froesch ER
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Growth hormone and insulin-like growth factor-I in odontogenesis
The International Journal of Developmental Biology, 1995This review documents recent insights into the roles of growth hormone and insulin-like growth factor-I during tooth formation. Hereditarily growth hormone-deficient Lewis dwarf rats and hypophysectomized rats have been used to document the influence of growth hormone on growth of the rat incisor and molar teeth in vivo.
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