Results 51 to 60 of about 18,925,600 (331)

Re-expression of IGF-II is important for beta cell regeneration in adult mice [PDF]

, 2012
Background The key factors which support re-expansion of beta cell numbers after injury are largely unknown. Insulin-like growth factor II (IGF-II) plays a critical role in supporting cell division and differentiation during ontogeny but its role in the
Nattkemper, Tim Wilhelm ; https://orcid.org/, Zhou Luxian, Abouna, Sylvie, Julia Herold (136338), James Young (44149), Nattkemper Tim Wilhelm, Abouna Sylvie, Nakhai Hassan, Epstein David, Tim Wilhelm Nattkemper, Herold Julia, Pelengaris Stella, Young, James, Khan, Michael, Stella Pelengaris, Herold, Julia, Nakhai, Hassan, Stella Pelengaris (71018), Hassan Nakhai (136340), Pelengaris, Stella, Sylvie Abouna (71019), Zhou, Luxian, Young James, Luxian Zhou, Michael Khan, Michael Khan (71023), Epstein, David, David Epstein, Luxian Zhou (136331), Hassan Nakhai, Khan Michael, Sylvie Abouna, Epstein, D. B. A., James Young, Nattkemper, Tim W., David Epstein (136335), Tim Wilhelm Nattkemper (136339), Julia Herold   +37 more
core   +2 more sources

Enhancement of memories by systemic administration of insulin-like growth factor II. [PDF]

Neuropsychopharmacology, 2014
To treat cognitive disorders in humans, new effective therapies that can be easily delivered systemically are needed. Previous studies showed that a bilateral injection of insulin-like growth factor II (IGF-II) into the dorsal hippocampus of rats or mice enhances fear memories and facilitates fear extinction.
Stern SA, Kohtz AS, Pollonini G, Alberini CM.   +3 more
europepmc   +4 more sources

Cell-free synthesis of rat insulin-like growth factor II [PDF]

Diabetes, 1982
Total RNA extracted from a rat liver cell line (BRL 3A) that synthesizes rat insulin-like growth factor II (IGF-II) was translated in a reticulocyte lysate cell-free system. Incubation of the translation products with antisera to mature rat IGF-II (Mr 8700) selectively immunoprecipitated a Mr 21,600 protein.
ACQUAVIVA, ANGELA MARIA, BRUNI C. B., NISSLEY S. P., AND RECHLER M. M.   +3 more
openaire   +3 more sources

Temporal expression pattern of the insulin-like growth factor II and fibroblast growth factor transcripts in avian embryogenesis

Brazilian Archives of Biology and Technology, 2008
In this study, the abundance of IGF-II and bFGF transcripts was estimated in the chicken embryos using the competitive RT-PCR analysis. Significant enhancements in the abundance of IGF-II mRNA were observed at stages HH1 and 5, and a new accumulation in ...
Jane Eyre Gabriel, Lúcia Elvira Alvares, Luiz Lehmann Coutinho   +2 more
doaj   +1 more source

Somatomedin-C/insulin-like growth factor-I and insulin-like growth factor-II mRNAs in rat fetal and adult tissues.

Journal of Biological Chemistry, 1986
Somatomedin-C or insulin-like growth factor I (Sm-C/IGF-I) and insulin-like growth factor II (IGF-II) have been implicated in the regulation of fetal growth and development.
P. K. Lund, B. Moats-Staats, Mary A. Hynes, James G. Simmons, M. Jansen, A. J. D'Ercole, J. V. van Wyk   +6 more
semanticscholar   +1 more source

Evolution of ancient functions in the vertebrate insulin-like growth factor system uncovered by study of duplicated salmonid fish genomes [PDF]

, 2013
This work was supported by the Marine Alliance for Science and Technology for Scotland pooling initiative, funded by the Scottish Funding Council (grant number HR09011) and contributing institutions.Whole genome duplication (WGD) was experienced twice by
Macqueen, Daniel J, MacQueen, Daniel John, de la Serrana, Daniel Garcia, Johnston, Ian Alistair, Garcia de la Serrana, Daniel, Garcia de la Serrana Castillo, Daniel, Johnston, Ian A, Johnston, Ian Alistair; id_orcid   +7 more
core   +1 more source

"Spontaneous" differentiation of skeletal myoblasts is dependent upon autocrine secretion of insulin-like growth factor-II.

Journal of Biological Chemistry, 1991
Differentiation of muscle cells to form postmitotic myotubes is usually viewed as being negatively controlled by medium components, sometimes designated "mitogens." However, we have found that a family of mitogenic agents, the insulin-like growth factors
J. Florini, K. A. Magri, D. Ewton, Payton L. James, K. Grindstaff, P. Rotwein   +5 more
semanticscholar   +1 more source

Liver mitochondrial dysfunction is reverted by insulin-like growth factor II (IGF-II) in aging rats

Journal of Translational Medicine, 2011
Background Serum IGF-I and IGF-II levels decline with age. IGF-I replacement therapy reduces the impact of age in rats. We have recently reported that IGF-II is able to act, in part, as an analogous of IGF-I in aging rats reducing oxidative damage in ...
Castilla-Cortazar Inma, Guerra Lucia, Puche Juan E, Sierra Inma, Garcia-Fernandez Maria   +4 more
doaj   +1 more source

Understanding IGF-II Action through Insights into Receptor Binding and Activation

Cells, 2020
The insulin-like growth factor (IGF) system regulates metabolic and mitogenic signaling through an intricate network of related receptors and hormones. IGF-II is one of several hormones within this system that primarily regulates mitogenic functions and ...
Andrew J. Blyth, Nicholas S. Kirk, Briony E. Forbes   +2 more
doaj   +1 more source

Erythropoiesis, serum erythropoietin, and serum IGF-I in rats during accelerated growth [PDF]

, 1990
In this study we have examined the correlation between activity of erythropoiesis and serum concentrations of erythropoietin and insulin-like growth factor I in male and female rats during accelerated growth (day 30-90).
Kurtz, Armin, Zapf, J., Matter, R., Eckardt, Kai-Uwe, J. Zapf, K.-U. Eckardt, A. Kurtz, Eckardt KU, Kurtz A, Matter R, Zapf J, R. Matter   +11 more
core   +1 more source