Results 31 to 40 of about 18,925,600 (331)

Understanding the mechanism of insulin and insulin-like growth factor (IGF) receptor activation by IGF-II. [PDF]

PLoS ONE, 2011
BACKGROUND: Insulin-like growth factor-II (IGF-II) promotes cell proliferation and survival and plays an important role in normal fetal development and placental function.
Clair L Alvino, Shee Chee Ong, Kerrie A McNeil, Carlie Delaine, Grant W Booker, John C Wallace, Briony E Forbes   +6 more
doaj   +1 more source

Determinants of IGF-II influencing stability, receptor binding and activation

Scientific Reports, 2022
Insulin like growth factor II (IGF-II) is involved in metabolic and mitogenic signalling in mammalian cells and plays important roles in normal fetal development and postnatal growth.
Andrew Blyth, Michael Ortiz, Allanah Merriman, Carlie Delaine, Briony Forbes   +4 more
doaj   +1 more source

Circulating Insulin-Like Growth Factor II and Colorectal Adenomas* [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2000
Abstract Circulating insulin-like growth factor I (IGF-I) and IGF-binding protein-3 (IGFBP-3) may be risk factors for the development of colorectal cancer. On the other hand, IGF-II and IGFBP-2 are overexpressed in colorectal carcinomas.
Renehan, Andrew G., Painter, John E., O'Halloran, Domhnall, Atkin, Wendy S., Potten, Christopher S., O'Dwyer, Sarah T., Shalet, Stephen M.   +6 more
openaire   +3 more sources

Gene expression patterns of insulin-like growth factor 1, insulin-like growth factor 2 and insulin-like growth factor binding protein 3 in human placenta from pregnancies with intrauterine growth restriction [PDF]

, 2011
Introduction: In this study, we compared insulin-like growth factor (IGF)-gene expression patterns and characteristics of glucose and insulin metabolism in human placenta from pregnancies with or without intrauterine growth restriction (IUGR).
Tóth, Katalin, Börzsönyi Balázs, Demendi Csaba, Balázs Börzsönyi, Börzsönyi, Balázs, Tóth Katalin, János Rigó Jr, Pajor, Attila, Rigó, János, Joó József, Gábor, Zsolt Nagy, Csaba Demendi, Rigó János, Pajor Attila, Mónika Csanád, Katalin Tóth, Demendi, Csaba, Csanád, Mónika, Nagy, Zsolt, Attila Pajor, József Gábor Joó, Nagy Zsolt, Csanád Mónika, Joó József Gábor   +23 more
core   +1 more source

Recurrent Severe Hypoglycemia Secondary to Benign Phyllodes Tumour of the Breast

Journal of the ASEAN Federation of Endocrine Societies, 2022
Non-Islet Cell Tumor-induced hypoglycemia (NICTH) secondary to phyllodes tumour is extremely rare but potentially life threatening if not treated promptly.
Hwee Ching Tee, Vijiya Mala Valayatham
doaj   +1 more source

Consequences of Postnatally Elevated Insulin-Like Growth Factor-II in Transgenic Mice: Endocrine Changes and Effects on Body and Organ Growth. [PDF]

, 1994
Insulin-like growth factor-II (IGF-II) is an important regulator of embryonic growth and differentiation, but its function in postnatal life is unclear. To address this point, we generated transgenic mice harboring fusion genes in which a human IGF-II
E. Wolf, Eckhard Wolf, Kramer, Rainer, Föll, Jürgen, Gottfried Brem, Brem, Gottfried, Wolf, Eckhard, Jijrgen Fijll, Blum, Werner F., Werner F. Blum, Rainer Kramer   +10 more
core   +2 more sources

Identification and characterization of insulin-like growth factor receptors on adult rat cardiac myocytes: linkage to inositol 1,4,5-trisphosphate formation. [PDF]

, 1992
Cultured cardiac myocytes from adult Sprague-Dawley rats express both insulin-like growth factor-I (IGF-I) receptors and insulin-like growth factor-II/mannose 6-phosphate (IGF-II/Man6P) receptors and respond to IGF-I with a dose-dependent accumulation of
Berg, Ingeborg, Guse, Andreas H., Kessler, Ulrike, Funk, Barbara, Gercken, Günther, A. H. Guse, Kiess, Wieland   +6 more
core   +2 more sources

IGF-II promotes neuroprotection and neuroplasticity recovery in a long-lasting model of oxidative damage induced by glucocorticoids

Redox Biology, 2017
Insulin-like growth factor-II (IGF-II) is a naturally occurring hormone that exerts neurotrophic and neuroprotective properties in a wide range of neurodegenerative diseases and ageing.
E. Martín-Montañez, C. Millon, F. Boraldi, F. Garcia-Guirado, C. Pedraza, E. Lara, L.J. Santin, J. Pavia, M. Garcia-Fernandez   +8 more
doaj   +1 more source

Estudio inmunocitoquímico y molecular de cultivo primario de tejido molar

Biomédica: revista del Instituto Nacional de Salud, 2006
Introducción. La enfermedad trofoblástica gestacional comprende un conjunto de patologías caracterizadas por crecimiento e invasión anómalos del trofoblasto.
Yinth Andrea Bernal, Luis Eduardo Díaz, Jinneth Acosta, Cecilia Crane, Stella Carrasco-Rodríguez, Antonio José Bermúdez, Myriam Sánchez-Gómez   +6 more
doaj   +1 more source

Immunohistochemical analysis of insulin‐like growth factor I, insulin‐like growth factor I receptor and insulin‐like growth factor II in endometriotic tissue and endometrium

Acta Obstetricia et Gynecologica Scandinavica, 1997
Background. The purpose of this study was to investigate unprecedentedly immunohistochemical localization of insulin‐like growth factor I, insulin‐like growth factor I receptor and insulin‐like growth factor II in endometriotic tissue, and to compare ...
Shiuh Y. Chang, Yat‐Sen Ho
doaj   +1 more source