Results 61 to 70 of about 408,308 (200)

A case of extragastrointestinal stromal tumor complicated by severe hypoglycemia: a unique presentation of a rare tumor [PDF]

, 2016
BACKGROUND: Non-Islet Cell Tumor Hypoglycemia (NICTH) is a rare paraneoplastic cause of hypoglycemia arising from excess tumor production of insulin-like growth factor.
Evans-Molina, Carmella, Saeed, Zeb, Taleb, Solaema   +2 more
core   +1 more source

The receptor for insulin-like growth factor II mediates an insulin-like response. [PDF]

The EMBO Journal, 1987
Insulin-like growth factor II (IGF-II) shares sequence homology and predicted three-dimensional structure with insulin and IGF-I. IGF-II can bind, therefore, to a limited extent with the receptors for these two other hormones, as well as to a distinct receptor for IGF-II.
J, Hari, S B, Pierce, D O, Morgan, V, Sara, M C, Smith, R A, Roth   +5 more
openaire   +2 more sources

The endocrinology of aging [PDF]

, 1997
Most aging individuals die from atherosclerosis, cancer, or dementia; but in the oldest old, loss of muscle strength resulting in frailty is the limiting factor for an individual's chances of living an independent life until death. Three hormonal systems
Beld, A.W. (Annewieke) van den, Lamberts, S.W.J. (Steven), Lely, A-J. (Aart-Jan) van der   +2 more
core   +1 more source

Genome-Wide Linkage Analysis to Identify Chromosomal Regions Affecting Phenotypic Traits in the Chicken. II. Body Composition [PDF]

, 2007
The current study is a comprehensive genome analysis to detect QTL affecting metabolic traits in chickens. Two unique F2 crosses generated from a commercial broiler male line and 2 genetically distinct inbred lines (Leghorn and Fayoumi) were used in the ...
Ashwell, C. M., Evock-Clover, C. M., Lamont, Susan, Lamont, Susan, McMurtry, J. P., Zhou, H.   +5 more
core   +5 more sources

Retroperitoneal Doege–Potter syndrome with intraoperative blood glucose monitoring

IJU Case Reports
Background Doege–Potter syndrome, characterized by solitary fibrous tumors and non‐islet cell tumor hypoglycemia, is rare. Here, we report a case of Doege–Potter syndrome in which retroperitoneal tumor resection was performed with continuous ...
Hirotaka Nagasaka, Takahisa Suzuki, Takuya Kondo, Mitsuyuki Koizumi, Hideyuki Terao, Yuko Murohashi, Yoichiro Okubo, Tomoyuki Yokose, Takeshi Kishida   +8 more
doaj   +1 more source

Insulin-like growth factor II gene Apa I polymorphism is not associated with endometriosis susceptibility

Genetics and Molecular Biology, 2004
Insulin-like growth factor II (IGF2) has been shown to play a role in abnormal cell growth and carcinogenesis. We investigated if the IGF2 gene Apa I polymorphism at exon 9 was associated with the susceptibility to endometriosis, analyzing 120 women with
Yao-Yuan Hsieh, Chi-Chen Chang, Fuu-Jen Tsai, Ching-Tien Peng, Lian-Shun Yeh, Cheng-Chieh Lin   +5 more
doaj   +1 more source

Insulin-like growth factor II signaling through the insulin-like growth factor II/mannose-6-phosphate receptor promotes exocytosis in insulin-secreting cells [PDF]

Proceedings of the National Academy of Sciences, 1997
The insulin-like growth factor II (IGF-II)/mannose-6-phosphate (M-6-P) receptor is known to participate in endocytosis as well as sorting of lysosomal enzymes and is involved in membrane trafficking through rapid cycling between cytosolic membrane compartments and the plasma membrane. Here we demonstrate that IGF-II, acting through the IGF-
Q, Zhang, M, Tally, O, Larsson, R T, Kennedy, L, Huang, K, Hall, P O, Berggren   +6 more
openaire   +2 more sources

Bioactive IGF-1 release from collagen-GAG scaffold to enhance cartilage repair in vitro. [PDF]

, 2015
Tissue engineering is a promising technique for cartilage repair. Toward this goal, a porous collagen-glycosaminoglycan (CG) scaffold was loaded with different concentrations of insulin-like growth factor-1 (IGF-1) and evaluated as a growth factor ...
Best, Serena M, Cameron, Ruth E, Ghose, Siddhartha, Mullen, Leanne M, Rushton, Neil, Wardale, John   +5 more
core   +2 more sources

Increasing Extraocular Muscle Strength with Insulin-like Growth Factor II

Investigative Ophthalmology & Visual Science, 2003
Botulinum toxin type A and, more recently, the immunotoxin ricin-mAb35 have been effective as means of pharmacologically weakening the extraocular muscle. However, currently there are no drug treatments to strengthen an underacting extraocular muscle. In limb muscle, treatment with insulin-like growth factor causes myofiber hypertrophy.
Linda K, McLoon, Stephen P, Christiansen
openaire   +2 more sources

β‐Galactosidase decreases the binding affinity of the insulin‐like‐growth‐factor‐II/mannose‐6‐phosphate receptor for insulin‐like‐growth‐factor II [PDF]

European Journal of Biochemistry, 1990
The insulin‐like growth‐factor‐II/mannose‐6‐phosphate (IGF‐II/Man6P) receptor binds two classes of ligands, insulin‐like growth factors and lysosomal enzymes. We have examined the ability of the lysosomal enzyme, β‐galactosidase, to modulate the binding of 125I‐IGF‐II to the receptor.
W, Kiess, C L, Thomas, M M, Sklar, S P, Nissley   +3 more
openaire   +2 more sources