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Pachydermoperiostosis Presenting With Gynecomastia and Low Insulin-Like Growth Factor-1 Levels: A Diagnostic Challenge. [PDF]
CureusAmith Priyansu J +4 more
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Associations between insulin-like growth factor 1, IGF-binding protein 3, and colorectal cancer. [PDF]
Cancer EpidemiolLawler T +5 more
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Correction to "Biologic Roles of Estrogen Receptor-β and Insulin-Like Growth Factor-2 in Triple-Negative Breast Cancer". [PDF]
Biomed Res Inteuropepmc +1 more source
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The Insulin-Like Growth Factors
Annual Review of Physiology, 1993"The insulin-like growth factors (IGF-I and IGF-II) are single-chain polypeptides with structural homology to proinsulin. They regulate proliferation and differentiation of a multitude of cell types and are capable of exerting insulin-like metabolic effects.
W S, Cohick, D R, Clemmons
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Annals of the New York Academy of Sciences, 1993
The purpose of this review has been to emphasize, in general terms, the major aspects of the structure, expression, and regulation of the IGF-I and IGF-II genes. The complex organization of these genes provides ample opportunities for control of gene expression at multiple levels.
D, LeRoith, C T, Roberts
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The purpose of this review has been to emphasize, in general terms, the major aspects of the structure, expression, and regulation of the IGF-I and IGF-II genes. The complex organization of these genes provides ample opportunities for control of gene expression at multiple levels.
D, LeRoith, C T, Roberts
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Insulin-Like Growth Factor Receptors
Growth Factors, 1991AbstractCompetitive binding experiments from a number of laboratories showed that IGF receptors are distinct from insulin receptors, and that there are two types of IGF receptors based on their relative affinities for IGF-I and IGF-II and whether or not they bind insulin (reviewed in Rechler and Nissley, 1985).
P, Nissley, W, Lopaczynski
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Insulin-like growth factor receptors
Journal of Cell Science, 1985ABSTRACT There are two types of insulin-like growth factor (IGF) receptors. The type I receptor generally binds IGF-I more tightly than IGF-II and also interacts weakly with insulin. The type II receptor prefers IGF-II over IGF-I and does not recognize insulin.
S P, Nissley +4 more
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Cell Biology International, 1995
ABSTRACTThe insulin‐like growth factors I and II are single chain polypeptides homologous to proinsulin. IGF I and IGF II contribute to cell regulation and stimulate protein synthesis via signaling through type I receptors which are homologous to insulin receptors and activate phosphorylation cascades.
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ABSTRACTThe insulin‐like growth factors I and II are single chain polypeptides homologous to proinsulin. IGF I and IGF II contribute to cell regulation and stimulate protein synthesis via signaling through type I receptors which are homologous to insulin receptors and activate phosphorylation cascades.
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Insulin-like growth factors in poultry
Domestic Animal Endocrinology, 1997A large amount of research, primarily in mammals, has defined to a great extent the pleiotropic effects of the IGF system on growth, development, and intermediary metabolism. Similar elucidations in poultry were hindered to some extent by the absence of native peptides (IGF-I and IGF-II) until their purification, followed by the production of ...
J P, McMurtry, G L, Francis, Z, Upton
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