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Cord blood levels of insulin-like growth factor-1 and insulin-like growth factor binding protein-3 correlate with perinatal brain development in fetal congenital heart disease. [PDF]

open access: yesUltrasound Obstet Gynecol
Nijman M   +12 more
europepmc   +1 more source

The Insulin-Like Growth Factors

Annual Review of Physiology, 1993
"The insulin-like growth factors (IGF-I and IGF-II) are single-chain polypeptides with structural homology to proinsulin. They regulate proliferation and differentiation of a multitude of cell types and are capable of exerting insulin-like metabolic effects.
W S, Cohick, D R, Clemmons
openaire   +2 more sources

Insulin‐like Growth Factors

Annals of the New York Academy of Sciences, 1993
The purpose of this review has been to emphasize, in general terms, the major aspects of the structure, expression, and regulation of the IGF-I and IGF-II genes. The complex organization of these genes provides ample opportunities for control of gene expression at multiple levels.
D, LeRoith, C T, Roberts
openaire   +2 more sources

Insulin-Like Growth Factor Receptors

Growth Factors, 1991
AbstractCompetitive binding experiments from a number of laboratories showed that IGF receptors are distinct from insulin receptors, and that there are two types of IGF receptors based on their relative affinities for IGF-I and IGF-II and whether or not they bind insulin (reviewed in Rechler and Nissley, 1985).
P, Nissley, W, Lopaczynski
openaire   +4 more sources

Insulin‐like growth factors.

Cell Biology International, 1995
ABSTRACTThe insulin‐like growth factors I and II are single chain polypeptides homologous to proinsulin. IGF I and IGF II contribute to cell regulation and stimulate protein synthesis via signaling through type I receptors which are homologous to insulin receptors and activate phosphorylation cascades.
openaire   +3 more sources

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